Your search returned 188 studies. (Get alerts for new studies):
- AFP464 in Treating Patients With Advanced Solid Tumors
Conditions: Breast Cancer - Kidney Cancer - Ovarian Cancer - Unspecified Adult Solid Tumor, Protocol Specific
1 Location available
- Safety Study of IHL-305 (Irinotecan Liposome Injection) to Treat Advanced Solid Tumors
Conditions: Cancer
2 Locations available
- E7389 and Cisplatin in Treating Patients With Advanced Solid Tumors
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
7 Locations available
- Bevacizumab and Bortezomib in Patients With Advanced Malignancy
Conditions: Advanced Malignancy - Lymphoma - Myeloma - Solid Tumors
1 Location available
- Valproic Acid-Based 2-Agent Oral Regimens for Patients With Advanced Solid Tumor
Conditions: Solid Tumors
1 Location available
- Sunitinib in Treating Patients With Unresectable or Metastatic Kidney Cancer or Other Advanced Solid Tumors
Conditions: Kidney Cancer - Unspecified Adult Solid Tumor, Protocol Specific
1 Location available
- Gossypol, Cisplatin, and Etoposide in Treating Patients With Advanced Solid Tumors or Extensive Stage Small Cell Lung Cancer
Conditions: Lung Cancer - Unspecified Adult Solid Tumor, Protocol Specific
5 Locations available
- Gemcitabine/Capecitabine/ZD6474 in Advanced Solid Tumors
Conditions: Advanced Solid Tumors - Biliary Cancer - Pancreatic Cancer
1 Location available
- Ipilimumab in Young Patients With Advanced or Refractory Solid Tumors
Conditions: Adult Malignant Fibrous Histiocytoma of Bone - Childhood Malignant Fibrous Histiocytoma of Bone - Kidney Cancer - Lymphoma - Melanoma (Skin) - Neuroblastoma - Sarcoma - Unspecified Adult Solid Tumor, Protocol Specific - Unspecified Childhood Solid Tumor,
3 Locations available
- A First In Patient, Study Of Investigational Drug PF-03446962 In Patients With Advanced Solid Tumors
Conditions: Advanced Solid Tumors
3 Locations available
- A Phase I/II Study of BEZ235 in Patients With Advanced Solid Malignancies Enriched by Patients With Advanced Breast Cancer
Conditions: Breast Cancer, - Advanced Solid Tumors, - Cowden Syndrome
8 Locations available
- Phase I Study of Vorinostat and Sorafenib in Advanced Cancer
Conditions: Advanced Solid Tumors
1 Location available
- A Dose Escalation Study of MK1775 in Combination With Either Gemcitabine, Cisplatin, or Carboplatin in Adults With Advanced Solid Tumors (MK-1775-001
Conditions: Solid Tumors
3 Locations available
- Study of Oral OSI-027 in Patients With Advanced Solid Tumors or Lymphoma
Conditions: Any Solid Tumor or Lymphoma
1 Location available
- Genotype-Directed Dose-Escalation Study of Irinotecan in Patients With Advanced Solid Tumors
Conditions: Advanced Cancer
1 Location available
- Phase I Safety Study of the Drug MM-121 in Patients With Advanced Solid Tumors Resisting Ordinary Treatment
Conditions: Advanced Solid Tumors
3 Locations available
- A Phase I/II Clinical Trial of Vidaza With Abraxane in the Treatment of Patients With Advanced or Metastatic Solid Tumors and Breast Cancer
Conditions: Advanced or Metastatic Solid Tumors - Advanced or Metastatic Breast Cancer
1 Location available
- FAU in Treating Patients With Advanced Solid Tumors or Lymphoma
Conditions: Lymphoma - Small Intestine Cancer - Unspecified Adult Solid Tumor, Protocol Specific
1 Location available
- A Phase 1b Study of AMG 386 in Combination With Either Pegylated Liposomal Doxorubicin or Topotecan in Subjects With Advanced Recurrent Epithelial Ova
Conditions: Cancer - Carcinoma - Fallopian Tube Cancer - Gynecological Malignancies - Metastases - Oncology - Ovarian Cancer - Solid Tumors - Tumors
8 Locations available
- A Phase 1 Study of AMG 208 in Subjects With Advanced Solid Tumors
Conditions: Cancer - Oncology - Tumors - Advanced Malignancy - Advanced Solid Tumors - Oncology Patients
3 Locations available
- Sunitinib and Hydroxychloroquine in Treating Patients With Advanced Solid Tumors That Have Not Responded to Chemotherapy
Conditions: Cancer
1 Location available
- A Study of QBI-139 in Subjects With Advanced Solid Tumors
Conditions: Solid Tumors
2 Locations available
- A Phase 1 First-in-Human Study Evaluating AMG 900 in Advanced Solid Tumors
Conditions: Advanced Malignancy - Advanced Solid Tumors - Cancer - Solid Tumors - Tumors
2 Locations available
- A Study of GDC-0941 in Patients With Locally Advanced or Metastatic Solid Tumors for Which Standard Therapy Either Does Not Exist or Has Proven Ineffe
Conditions: Solid Cancers
3 Locations available
- A Trial In Patients With Advanced Cancer And Leukemia
Conditions: Neoplasms by Histologic Type - Leukemia, Lymphoid - Leukemia, T-Cell - Solid Tumors
6 Locations available
- Dose Finding and Safety of Oral LDE225 in Patients With Advanced Solid Tumors
Conditions: Advanced Solid Tumor Cancers - Medulloblastoma - Basal Cell Carcinoma
2 Locations available
- Ixabepilone and Sunitinib Malate in Treating Patients With Progressive Advanced Solid Tumors
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
1 Location available
- Dose-escalation Study of Oral CX-4945
Conditions: Advanced Solid Tumors - Breast Cancer - Inflammatory Breast Cancer - Castleman's Disease - Multiple Myeloma
4 Locations available
- Methoxyamine and Temozolomide in Treating Patients With Advanced Solid Tumors
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
1 Location available
- A Dose Escalation Study of SF1126, a PI3 Kinase (PI3K) Inhibitor, Given By Intravenous (IV) Infusion in Patients With Solid Tumors
Conditions: Advanced or Metastatic Solid Tumors - Cancer - Solid Cancers
4 Locations available
- Combination Study of BMS-754807 and Erbitux® in Subjects With Advanced or Metastatic Solid Tumors
Conditions: Colorectal Cancer - Head and Neck Cancer - Neoplasm Metastasis
3 Locations available
- Lung Function Testing in Patients With Locally Advanced or Metastatic Solid Tumors
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
1 Location available
- A Safety Study Of A Monoclonal Antibody Against A5B1 Integrin In Solid Tumors
Conditions: Advanced Non-Hematologic Malignancies
4 Locations available
- Phase I and Pharmacology Study of Camptothecin-20-O-Propionate Hydrate (CZ48) in Patients With Solid Tumors or Lymphoma
Conditions: Advanced Solid Tumors - Lymphomas
2 Locations available
- A Study of the Safety and Pharmacology of GDC-0941 in Combination With Erlotinib in Patients With Advanced Solid Tumors
Conditions: Non-Small Cell Lung Cancer, Solid Cancers
2 Locations available
- Study of AR-12 (2-Amino-N-[4-[5-(2 Phenanthrenyl)-3-(Trifluoromethyl)-1H-pyrazol-1-yl] Phenyl]-Acetamide) in Adult Patients With Advanced or Recurrent
Conditions: Solid Tumors - Lymphoma
2 Locations available
- Study to Evaluate Panobinostat (DACi) Pharmacokinetics and Safety in Solid Tumors and Varying Renal Function
Conditions: Advanced Solid Tumors
1 Location available
- A Study of Oral Sapacitabine and Oral Seliciclib in Patients With Advanced Solid Tumors
Conditions: Advanced Solid Tumors
1 Location available
- A Dose Escalation Study in Adult Patients With Advanced Solid Malignancies
Conditions: Advanced Solid Tumors With FGFR1 Amplication, - Advanced Solid Tumors With FGFR2 Amplication, - Advanced Solid Tumors With FGFR3 Mutation
7 Locations available
- Pharmacokinetics and Safety of Panobinostat in Patients With Advanced Solid Tumors and Various Degrees of Hepatic Function
Conditions: Advanced Solid Tumors
1 Location available
- A Study of Intravenous XMT-1107 in Patients With Advanced Solid Tumors
Conditions: Advanced Solid Tumors
4 Locations available
- ABT-888 and Topotecan Hydrochloride in Treating Patients With Advanced Solid Tumors or Relapsed or Refractory Ovarian Epithelial Cancer or Primary Per
Conditions: Ovarian Cancer - Primary Peritoneal Cavity Cancer - Unspecified Adult Solid Tumor, Protocol Specific
3 Locations available
- Study of NMS-1286937 in Adult Patients With Advanced/Metastatic Solid Tumors
Conditions: Advanced or Metastatic Solid Tumors
1 Location available
- First-in-Man, Dose-escalation Trial of C-met Kinase Inhibitor EMD 1214063 in Subjects With Advanced Solid Tumors
Conditions: Patients With Solid Tumors, Either Refractory to Standard Therapy or for Which no Effective Standard Therapy is Available
1 Location available
- Study of NMS-1116354 in Solid Tumors
Conditions: Advanced Solid Tumors
1 Location available
- A Combination Therapy Study of MK2206 and AZD6244 in Participants With Advanced Solid Tumors (MK-2206-010 AM5)
Conditions: Locally Advanced or Metastatic Solid Tumors
2 Locations available
- Hydroxychloroquine + Vorinostat in Advanced Solid Tumors
Conditions: Advanced Solid Tumor
1 Location available
- A Study of Temsirolimus Plus Capecitabine in Patients With Advanced Cancer
Conditions: Advanced Solid Tumors
1 Location available
- Dose-Escalation Phase 1 Study of G-202 in Patients With Advanced Solid Tumors
Conditions: Advanced Solid Tumors
3 Locations available
- A Trial of AMG 479, Everolimus (RAD001) and Panitumumab in Patients With Advanced Cancer
Conditions: Advanced Solid Tumors
1 Location available
- Trial of Bi-shRNA-furin and Granulocyte Macrophage Colony Stimulating Factor (GMCSF) Augmented Autologous Tumor Cell Vaccine for Advanced Cancer
Conditions: Solid Tumors
1 Location available
- A Study of ABT-888 in Combination With Carboplatin and Gemcitabine in Subjects With Advanced Solid Tumors
Conditions: Advanced Solid Tumors
6 Locations available
- Dose Escalation Study of Safety and Tolerability of AT-406 in Patients With Advanced Solid Tumors and Lymphomas
Conditions: Cancer - Solid Tumors - Lymphoma - Malignancy
3 Locations available
- Calcitriol, Cisplatin, and Gemcitabine Hydrochloride in Treating Patients With Advanced Solid Tumors That Cannot Be Removed By Surgery
Conditions: Advanced Solid Tumors
1 Location available
- A Phase 1 Study of MLN8237 in Patients With Advanced Solid Tumors Including Castration-Resistant Prostate Cancer Receiving a Standard Docetaxel Regime
Conditions: Advanced Solid Tumors - Adenocarcinoma of the Prostate
1 Location available
- A Phase I/II Study of Paclitaxel, Carboplatin and YM155 (Survivin Suppressor) in Subjects With Solid Tumors (Phase I) and Advanced Non-Small Cell Lung
Conditions: NSCLC - Solid Tumors
1 Location available
- A Dose Finding and Safety Study of Oral LEQ506 in Patients With Advanced Solid Tumors
Conditions: Advanced Solid Tumors - Recurrent or Refractory Medulloblastoma - Locally Advanced or Metastatic Basal Cell Carcinoma
2 Locations available
- A Study Evaluating the Safety, Tolerability, and Pharmacokinetics of GDC-0623 in Patients With Locally Advanced or Metastatic Solid Tumors
Conditions: Solid Cancers
3 Locations available
- First-in-Man, Dose-escalation Trial of c-Met Kinase Inhibitor EMD 1204831 in Subjects With Advanced Solid Tumors
Conditions: Solid Tumors
1 Location available
- ABT-348 as Monotherapy or Combination With Carboplatin or Docetaxel to Treat Advanced Solid Tumors
Conditions: Advanced Solid Tumors
2 Locations available
- Vorinostat and Lapatinib in Advanced Solid Tumors and Advanced Breast Cancer to Evaluate Response and Biomarkers
Conditions: Breast Cancer - Neoplasm Metastasis
1 Location available
- A Study of IMC-RON8 in Advanced Solid Tumors
Conditions: Cancer
2 Locations available
- A Pilot Study of EZN-2968, an Antisense Oligonucleotide Inhibitor of HIF-1alpha, in Adults With Advanced Solid Tumors With Liver Metastases
Conditions: Neoplasms - Liver Metastases
1 Location available
- Study of RAD001 + AMG479 for Patients With Advanced Solid Tumors
Conditions: Neoplasm Metastases
1 Location available
- Cilengitide and Sunitinib Malate in Treating Patients With Advanced Solid Tumors or Glioblastoma Multiforme
Conditions: Brain and Central Nervous System Tumors - Unspecified Adult Solid Tumor, Protocol Specific
1 Location available
- A Phase 1 Dose Escalation Study of AMG 780 in Adult Subjects With Advanced Solid Tumor
Conditions: Advanced Solid Tumors
2 Locations available
- Safety and Pharmacokinetic Study of Cabazitaxel in Patients With Advanced Solid Tumors and Liver Impairment
Conditions: Neoplasm Malignant
13 Locations available
- ABT-888 and Gemcitabine Hydrochloride in Treating Patients With Advanced Solid Tumors
Conditions: brca1 Mutation Carrier - brca2 Mutation Carrier - Unspecified Adult Solid Tumor, Protocol Specific
1 Location available
- A Study to Investigate Safety, Pharmacokinetics (PK) and Pharmacodynamics (PD) of BKM120 Plus GSK1120212 in Selected Advanced Solid Tumor Patients
Conditions: Advanced and Selected Solid Tumors
2 Locations available
- Bioavailability and Food Effect Study of TKI258 (CSF Capsule vs. FMI Tablet) in Adult Patients With Advanced Solid Tumors
Conditions: Neoplasm - Cancer - Tumors
4 Locations available
- Safety Study of AB0024 in Patients With Advanced Solid Tumors
Conditions: Solid Tumors - Cancer
2 Locations available
- Entinostat and Sorafenib Tosylate in Treating Patients With Advanced or Metastatic Solid Tumors or Refractory or Relapsed Acute Myeloid Leukemia
Conditions: Leukemia - Unspecified Adult Solid Tumor, Protocol Specific
2 Locations available
- Study of PEGPH20 With Initial Dexamethasone Premedication Given Intravenously to Patients With Advanced Solid Tumors
Conditions: Solid Tumor
5 Locations available
- Pemetrexed Disodium and Docetaxel in Treating Patients With Advanced Solid Tumors
Conditions: Breast Cancer - Esophageal Cancer - Gastric Cancer - Head and Neck Cancer - Lung Cancer - Ovarian Cancer - Prostate Cancer
1 Location available
- Study to Assess Safety, Pharmacokinetics, and Efficacy of Oral CC-223 for Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma or Multiple Myelom
Conditions: Multiple Myeloma - Diffuse Large B-Cell Lymphoma - Glioblastoma Multiforme - Hepatocellular Carcinoma - Non-Small Cell Lung Cancer - Gastrointestinal Neuroendocrine Tumors of Non-Pancreatic Origin - Hormone Receptor-Positive Breast Cancer
8 Locations available
- An Extension Protocol for Subjects Who Were Previously Enrolled in Other ARQ 197 Protocols
Conditions: Advanced Solid Tumors
5 Locations available
- Pazopanib and Everolimus in Patients With Advanced Solid Tumors and Previously Treated Kidney Cancer
Conditions: Solid Tumor - Kidney Cancer
2 Locations available
- Dose Escalation, Combination Chemotherapy Safety Study of TL32711, in Subjects With Advanced or Metastatic Solid Tumors
Conditions: Cancer
6 Locations available
- A Study of PNT2258 in Patients With Advanced Solid Tumors
Conditions: Cancer - Lymphoma - Prostate - Melanoma
1 Location available
- Hormone Blockade in Combination With Targeted Agents
Conditions: Solid Tumors - Advanced Cancer
1 Location available
- Study of Intravenous TCD-717 in Patients With Advanced Solid Tumors
Conditions: Advanced Solid Tumors
1 Location available
- MEK Inhibitor AZD6244 and Cetuximab Treating Patients With Advanced or Refractory Solid Tumors That Cannot Be Removed By Surgery
Conditions: Colorectal Cancer - Unspecified Adult Solid Tumor, Protocol Specific
1 Location available
- A Study of BYL719 in Adult Patients With Advanced Solid Malignancies, Whose Tumors Have an Alteration of the PIK3CA Gene
Conditions: Advanced Solid Tumors - With an Alteration of the PIK3CA Gene
4 Locations available
- Dose Escalation Study of ARQ 736 in Adult Subjects With Advanced Solid Tumors Harboring BRAF and/or NRAS Mutations
Conditions: Solid Tumor
3 Locations available
- A Study of the Hsp90 Inhibitor AUY922 Plus Capecitabine for the Treatment of Patients With Advanced Solid Tumors
Conditions: Metastatic or Unresectable Solid Tumor Malignancy
3 Locations available
- GAMMA - Gemcitabine and AMG 479 in Metastatic Adenocarcinoma of the Pancreas
Conditions: Adenocarcinoma of the Pancreas - Advanced Solid Tumors - Cancer - Cancer of Pancreas - Cancer of the Pancreas - Metastases - Metastatic Cancer - Metastatic Pancreatic Cancer - Pancreas Cancer - Pancreatic Cancer - Bone Metastases - Endocrine Cancer - Onco
20 Locations available
- MK-2206, Paclitaxel and Trastuzumab in Treating Patients With HER2-overexpressing Solid Tumor Malignancies
Conditions: Advanced Solid Tumors - Tumors - Cancer
1 Location available
- A Trial of LEE011 in Patients With Advanced Solid Tumors or Lymphoma
Conditions: Advanced Solid Tumor - Lymphomas
3 Locations available
- A Study to Test Safety and Efficacy of IMGN901 in Combination With Carboplatin/Etoposide in Patients With Advanced Solid Tumors and Extensive Stage Sm
Conditions: Small Cell Lung Cancer and Other Solid Tumors
2 Locations available
- Study of NK012 and 5-FU/LV in Solid Tumors Followed by Dose Expansion in Colorectal Cancer
Conditions: Advanced Solid Tumors - Metastatic Colorectal Cancer
1 Location available
- An Early Phase I Study of IPdR Absorption, Metabolism, and Safety in Patients With Advanced Solid Tumors and Lymphomas
Conditions: Neoplasms - Lymphoma
1 Location available
- A Study of LCL161 in Combination With Weekly Paclitaxel in Adult Patients With Advanced Solid Tumors
Conditions: Solid Tumors
3 Locations available
- A Study to Evaluate the Safety and Antitumor Activity in Subjects With Advanced Solid Tumor
Conditions: Advanced Solid Tumors
5 Locations available
- A Study of AMG 337 in Subjects With Advanced Solid Tumors
Conditions: Advanced Malignancy - Advanced Solid Tumors - Cancer - Oncology - Oncology Patients - Tumors
4 Locations available
- A Study of ABT-806 in Subjects With Advanced Solid Tumor Types
Conditions: Advanced Solid Tumors
3 Locations available
- MK2206 and Paclitaxel in Treating Patients With Locally Advanced or Metastatic Solid Tumors or Metastatic Breast Cancer
Conditions: Breast Cancer - Unspecified Adult Solid Tumor, Protocol Specific
3 Locations available
- Cilengitide and Paclitaxel in Treating Patients With Advanced Solid Tumors
Conditions: Breast Cancer - Unspecified Adult Solid Tumor, Protocol Specific
2 Locations available
- Study of Anti-HB-EGF Antibody KHK2866 in Subjects With Advanced Solid Tumors and Ovarian Cancer
Conditions: Neoplasms - Ovarian Neoplasms - Fallopian Tube Neoplasms - Primary Peritoneal Neoplasm
5 Locations available
- Study of GO-203-2C Given Intravenously in Patients With Advanced Solid Tumors
Conditions: Solid Tumors
3 Locations available
- Veliparib in Combination With Carboplatin and Paclitaxel in Treating Patients With Locally Advanced or Metastatic Solid Tumors
Conditions: Breast Cancer - Unspecified Adult Solid Tumor, Protocol Specific
2 Locations available
- High-Dose or Low-Dose Vorinostat in Combination With Carboplatin in Treating Patients With Advanced Solid Tumors
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
1 Location available
- Study of an Investigational Drug, ASP3026, in Patients With Advanced Malignancies (Solid Tumors and B-Cell Lymphoma)
Conditions: Advanced Malignancies - B-Cell Lymphoma - Solid Tumor
2 Locations available
- Study of BMN 673, a PARP Inhibitor, in Patients With Advanced or Recurrent Solid Tumors
Conditions: Advanced or Recurrent Solid Tumors
2 Locations available
- A Study of DS-2248, in Subjects With Advanced Solid Tumors
Conditions: Solid Tumors - Non-small Cell Lung Carcinoma
2 Locations available
- A Study of Anti-VEGFR-3 Monoclonal Antibody IMC-3C5 in Subjects With Advanced Solid Tumors
Conditions: Neoplasms
2 Locations available
- Study to Assess the Safety and Tolerability of U3-1565 in Subjects With Advanced Solid Malignant Tumors
Conditions: Advanced Solid Malignant Tumors - Advanced Ovarian Cancer
4 Locations available
- Study to Evaluate the Safety and Tolerability of Weekly IV Doses of BMS-906024 in Subjects With Advanced or Metastatic Solid Tumors
Conditions: Cancer
2 Locations available
- A Dose Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Patients With Locally Advanced or Metastatic Solid Tumors
Conditions: Solid Cancers
3 Locations available
- Safety Study of X-82 in Patients With Advanced Solid Tumors
Conditions: Advanced Solid Tumors
2 Locations available
- BKM120 + Carboplatin + Paclitaxel for Patients With Advanced Solid Tumors
Conditions: Solid Tumors
1 Location available
- Study of PM060184 in Patients With Advanced Solid Tumors
Conditions: Solid Tumors
1 Location available
- A Study of BIND-014 Given to Patients With Advanced or Metastatic Cancer
Conditions: Metastatic Cancer - Cancer - Solid Tumors
3 Locations available
- Safety and Efficacy Study of PRI-724 in Subjects With Advanced Solid Tumors
Conditions: Advanced Solid Tumors
1 Location available
- Riluzole and Sorafenib Tosylate in Treating Patients With Advanced Solid Tumors or Melanoma
Conditions: Cutaneous Melanoma - Unspecified Adult Solid Tumor, Protocol Specific
1 Location available
- A Trial of Tivozanib (AV-951) in Combination With Capecitabine (Xeloda®) in Subjects With Advanced Solid Tumors
Conditions: Advanced Solid Tumors - Locally Advanced or Metastatic Breast or Colorectal Cancer
3 Locations available
- Safety Study of Adenovirus/PNP Coupled With Fludarabine Phosphate to Treat Solid Tumors
Conditions: Head and Neck Cancer - Advanced Solid Tumors
1 Location available
- Evaluation of Safety, Tolerability, PK & PD of Intravenous VX15/2503 in Patients With Advanced Solid Tumors
Conditions: Solid Tumors
2 Locations available
- A Study of ALT-836 in Combination With Gemcitabine for Locally Advanced or Metastatic Solid Tumors
Conditions: Locally Advanced Malignant Neoplasm - Malignant Solid Tumour
4 Locations available
- Veliparib, Bendamustine Hydrochloride, and Rituximab in Treating Patients With Advanced Lymphoma, Multiple Myeloma, or Solid Tumors
Conditions: Lymphoma - Multiple Myeloma and Plasma Cell Neoplasm - Precancerous Condition - Small Intestine Cancer - Unspecified Adult Solid Tumor, Protocol Specific
1 Location available
- A Pharmacokinetic Study of AMG 386 in Cancer Subjects With Normal and Impaired Renal Function
Conditions: Advanced Solid Tumors - Kidney Disease - Renal Impairment
4 Locations available
- GDC-0980 in Combination With a Fluoropyrimidine, Oxaliplatin, and Bevacizumab in Patients With Advanced Solid Tumors
Conditions: Solid Cancers
3 Locations available
- Study of TRC105 Combined With Standard-Dose Bevacizumab for Advanced Solid Tumors for Which Bevacizumab is Indicated
Conditions: Adult Solid Tumor
4 Locations available
- Study of PI3 Kinase/mTOR Inhibitor BEZ235 Twice Daily for Advanced Solid Tumors
Conditions: Solid Tumor Malignancy
2 Locations available
- A Study of IMC-CS4 in Subjects With Advanced Solid Tumors
Conditions: Neoplasms
3 Locations available
- MEK162 and RAF265 in Adult Patients With Advanced Solid Tumors Harboring RAS or BRAFV600E Mutations
Conditions: Advanced Solid Tumors
3 Locations available
- Gemcitabine, Carboplatin, and Lenalidomide for Treatment of Advanced/Metastatic Urothelial Cancer and Other Solid Tumors
Conditions: Urethral Neoplasms - Neoplasms, Urethral - Ureter Cancer - Cancer of the Urethra - Urethral Cancer
1 Location available
- Study to Assess Safety and Tolerability of Oral CC-115 for Patients With Advanced Solid Tumors, Non-Hodgkin's Lymphoma or Multiple Myeloma
Conditions: Multiple Myeloma - Non-Hodgkin's Lymphoma - Glioblastoma Multiforme - Head and Neck Squamous Cell Cancer - Triple Negative Breast Cancer - Hormone Receptor-Positive Breast Cancer - Castration-Resistant Prostate Cancer - Ewing's Family of Sarcomas
2 Locations available
- E7050 in Combination With Cisplatin and Capecitabine Versus Cisplatin and Capecitabine Alone in Patients With Advanced or Metastatic Solid Tumors and
Conditions: Advanced or Metastatic Solid Tumors - Previously Untreated Gastric Cancer
2 Locations available
- Evaluating the Safety and Tolerability of GDC-0349 in Patients With Locally Advanced or Metastatic Solid Tumors or Non Hodgkin's Lymphoma
Conditions: Non-Hodgkin's Lymphoma - Solid Tumour
1 Location available
- Oral SAR245408 (XL147) and Oral MSC1936369B in Patients With Locally Advanced or Metastatic Solid Tumors
Conditions: Solid Tumors
3 Locations available
- A Study of the Safety, Tolerability, and Efficacy of SCH 900353 in Participants With Advanced Solid Tumors (P06203 AM2)
Conditions: Tumor, Solid
3 Locations available
- A Study of RO5429083 in Patients With Metastatic and/or Locally Advanced, CD44-Expressing, Malignant Solid Tumors
Conditions: Neoplasms
2 Locations available
- Trial Evaluating the Safety and Pharmacokinetics of MFGR1877S in Patients With Advanced Solid Tumors
Conditions: Solid Tumour
5 Locations available
- Safety, Pharmacokinetics and Pharmacodynamics of BKM120 Plus MEK162 in Selected Advanced Solid Tumor Patients
Conditions: Advanced Solid Tumors, - Selected Solid Tumors
3 Locations available
- Safety and Tolerability of DS-7423 in Subjects With Advanced Solid Malignant Tumors
Conditions: Solid Tumor - Colorectal Cancer - Endometrial Cancer
3 Locations available
- Ginseng on Cancer-Related Fatigue
Conditions: Advanced Cancers - Solid Tumors
1 Location available
- Dose-Escalation Safety and Pharmacokinetic Study of Iso-Fludelone in Patients With Advanced Solid Tumors
Conditions: Solid Tumors
1 Location available
- A Phase II Study to Evaluate the Efficacy of TKI258 for the Treatment of Patients With FGFR2 Mutated or Wild-type Advanced and/or Metastatic Endometri
Conditions: Solid Tumors and Advanced Endometrial Cancer - Endometrial Cancer - Second-line Treatment - VEGF
2 Locations available
- Trial of MEK Inhibitor and PI3K/mTOR Inhibitor in Subjects With Locally Advanced or Metastatic Solid Tumors
Conditions: Locally Advanced Solid Tumor - Metastatic Solid Tumor - Breast Cancer - Non Small Cell Lung Cancer - Melanoma - Colorectal Cancer
2 Locations available
- Study of PM01183 in Non-Colorectal Cancer Patients as a Days 1 and 8 Intravenous Short Infusion Every 3 Weeks
Conditions: Major Advanced Solid Tumors Other Than Colorectal
1 Location available
- An Extension Study of ABT-806 in Subjects With Advanced Solid Tumors
Conditions: Advanced Solid Tumors
1 Location available
- Study of Pazopanib, Paclitaxel, and Carboplatin in Patients With Advanced Solid Tumors
Conditions: Unspecified Adult Solid Tumor - Protocol Specific - Breast Cancer - Female
1 Location available
- An Extension Study of Linifanib (ABT-869) in Subjects With Advanced or Metastatic Solid Tumors
Conditions: Advanced Solid Tumors
3 Locations available
- Dose Escalation Study of NKP-1339 to Treat Advanced Solid Tumors
Conditions: Solid Tumors
2 Locations available
- Bioequivalence of 2 Formulations of TKI258 in Patients With Advanced Solid Tumors
Conditions: Advanced Solid Tumors - Excluding Breast Cancer
7 Locations available
- Study of CC-122 to Evaluate the Safety, Tolerability, and Effectiveness for Patients With Advanced Solid Tumors, Non-Hodgkin's Lymphoma, or Multiple M
Conditions: Solid Tumors - Non-Hodgkin's Lymphoma - Multiple Myeloma
2 Locations available
- Pazopanib and Everolimus in PI3KCA Mutation Positive/PTEN Loss Patients
Conditions: Advanced Cancers - Solid Tumors
1 Location available
- Study of Dalotuzumab Alone and With Ridaforolimus in Pediatric Participants With Advanced Solid Tumors (MK-8669-062 AM1)
Conditions: Solid Tumors
1 Location available
- Safety and Pharmacology of GDC-0068 in Combination With Either Docetaxel or Fluoropyrimidine Plus Oxaliplatin in Patients With Advanced Solid Tumors
Conditions: Solid Cancers
2 Locations available
- E7050 in Combination With E7080 in Subjects With Advanced Solid Tumors (Dose Escalation) and in Subjects With Recurrent Glioblastoma or Unresectable S
Conditions: Advanced Solid Tumors
1 Location available
- Veliparib and Dinaciclib With or Without Carboplatin in Treating Patients With Advanced Solid Tumors
Conditions: brca1 Mutation Carrier - brca2 Mutation Carrier - Unspecified Adult Solid Tumor, Protocol Specific
1 Location available
- Study Determining the Safety and Tolerability of Combination Therapy With Pazopanib and GSK1120212 in Advanced Solid Tumors Enriched With Patients Wit
Conditions: Solid Tumors - Advanced Thyroid Cancer
2 Locations available
- Phase I Study to Determine the Maximum Tolerable Dose of BAY94-9343 in Patients With Advanced Solid Tumors.
Conditions: Oncology
3 Locations available
- Dasatinib in Combination With Bevacizumab to Treat Advanced Solid Tumors
Conditions: Solid Tumors
1 Location available
- Safety Study of MM-121 in Combination With Multiple Anticancer Therapies in Patients With Advanced Solid Tumors
Conditions: Solid Tumors
4 Locations available
- Phase 1 Study of CEP-37250/KHK2804 in Subjects With Advanced Solid Tumors
Conditions: Solid Tumour - Adenocarcinoma of the Colon - Adenocarcinoma of the Pancreas
3 Locations available
- A Phase Ib Study of MEK162 Plus BYL719 in Adult Patients With Selected Advanced Solid Tumors
Conditions: Advanced and Selected Solid Tumors
2 Locations available
- Pemetrexed Disodium and Sorafenib Tosylate in Treating Patients With Advanced Solid Tumors
Conditions: Unspecified Adult Solid Tumor
1 Location available
- Dose Escalation Study of INK1117 in Subjects With Advanced Cancer
Conditions: Metastatic Solid Tumors
1 Location available
- Pazopanib, Lapatinib or Trastuzumab in Subjects With Solid Tumors
Conditions: Advanced Cancers
1 Location available
- A Study of LY2812176 in Multiple Myeloma or Advanced Solid Tumors
Conditions: Multiple Myeloma - Solid Tumors
1 Location available
- An A/B Dose Escalation Study of AbGn-7 Alone and With FOLFOX7 Treatment in Patients With Advanced Solid Tumors
Conditions: Solid Tumor of Epithelial Origin - Gastric Cancer
1 Location available
- Pazopanib and ARQ 197 for Advanced Solid Tumors
Conditions: Sarcoma - Stomach Neoplasms - Neoplasms
1 Location available
- Safety, Tolerability, Pharmacokinetics, and Immunoregulatory Study of BMS-663513 in Subjects With Advanced and/or Metastatic Solid Tumors
Conditions: Cancer - Solid Tumors
4 Locations available
- Study of ABT-700 in Subjects With Advanced Solid Tumors
Conditions: Subjects With Advanced Solid Tumors (Including, But Not Limited to Gastric, Head and Neck, NSCLC, Colon, Mesothelioma and Triple Negative Breast Cancer).
3 Locations available
- Phase 1 Dose Escalation Study of ARQ 092 in Adult Subjects With Advanced Solid Tumors
Conditions: Solid Tumor
1 Location available
- A Phase I/IIa, First Time in Human, Study of GSK2636771 in Subjects With Advanced Solid Tumors With Phosphatase and Tensin Homolog (PTEN) Deficiency
Conditions: Cancer
2 Locations available
- BAY 94-9343 for Advanced Solid Tumors
Conditions: Mesothelioma - Ovarian Neoplasms - Pancreatic Neoplasms - Neoplasm
1 Location available
- Dose Finding Study of RAD001 (Everolimus, Afinitor®) in Combination With BEZ235 in Patients With Advanced Solid Tumors
Conditions: Advanced Solid Tumors - Metastatic Breast Cancer - Metastatic Renal Cell Carcinoma
1 Location available
- Akt Inhibitor MK2206 and Hydroxychloroquine in Treating Patients With Advanced Solid Tumors or Prostate or Kidney Cancer
Conditions: Kidney Cancer - Prostate Cancer - Unspecified Adult Solid Tumor, Protocol Specific
1 Location available
- ABC294640 in Treating Patients With Advanced Solid Tumors
Conditions: Pancreatic Cancer - Unspecified Adult Solid Tumor, Protocol Specific
1 Location available
- Phase Ib Study of Gemcitabine Plus Cisplatin or Carboplatin Plus Dovitinib in Patients With Advanced Solid Tumors
Conditions: Solid Tumors - Bladder Cancer
1 Location available
- Dovitinib Lactate, Gemcitabine Hydrochloride, and Capecitabine in Treating Patients With Advanced or Metastatic Solid Tumors or Advanced Pancreatic Ca
Conditions: Adenocarcinoma of the Pancreas - Stage III Pancreatic Cancer - Stage IV Pancreatic Cancer - Unspecified Adult Solid Tumor, Protocol Specific
1 Location available
- Lapatinib and Bortezomib in Patients With Advanced Malignancies
Conditions: Advanced Solid Tumors
1 Location available
- Phase I Intratumoral Pbi-shRNA STMN1 LP in Advanced and/or Metastatic Cancer
Conditions: Advanced Cancer - Metastatic Cancer - Solid Tumors
1 Location available
- Study of VGX-100 Administered Alone and Co-administered With Bevacizumab in Adult Subjects With Advanced Solid Tumors
Conditions: Neoplasms - Cancer
2 Locations available
- Safety Study of the Drug MM-151 in Patients With Advanced Solid Tumors Resisting Ordinary Treatment
Conditions: Advanced Solid Tumors
4 Locations available
- Safety Study of PLX3397 and Paclitaxel in Patients With Advanced Solid Tumors
Conditions: Advanced, Incurable Solid Tumors
1 Location available
- CBLB502 in Treating Patients With Locally Advanced or Metastatic Solid Tumors That Cannot Be Removed By Surgery
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
1 Location available
- A Study to Look at How a Single Oral Dose of 14C-OSI-906 is Absorbed, Broken Down and Eliminated in the Body
Conditions: Advanced Solid Tumors - Pharmacokinetics of 14C-OSI-906
1 Location available
- Erlotinib in Combination With Pralatrexate in Advanced Malignancies
Conditions: Advanced Cancers - Solid Tumors
1 Location available
- A Phase I Study of BKM120 and Everolimus in Advanced Solid Malignancies
Conditions: Solid Tumors
1 Location available
- Pazopanib Hydrochloride in Treating Patients With Advanced or Refractory Solid Tumors
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
2 Locations available
- FdCyd and THU for Advanced Solid Tumors
Conditions: Neoplasms
7 Locations available
- A Dose Escalation Study of Hydroxyurea in Combination With SCH900776 in Advanced Malignant Solid Tumors
Conditions: Advanced Solid Tumors
1 Location available
- MSC2015103B in Solid Tumors
Conditions: Advanced Solid Tumor
3 Locations available
- Gemcitabine Hydrochloride and Smac Mimetic TL32711 in Treating Patients With Advanced Solid Tumors
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
1 Location available
- A Open-Label, Multiple Ascending Dose Study of DS-3078a, an Oral TORC1/2 Kinase Inhibitor, in Subjects With Advanced Solid Tumors or Lymphomas
Conditions: Advanced Solid Tumor - Lymphoma
1 Location available
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