Your search returned 56 studies. (Get alerts for new studies):
- A Phase I/II Study of BEZ235 in Patients With Advanced Solid Malignancies Enriched by Patients With Advanced Breast Cancer
Conditions: Breast Cancer, - Advanced Solid Tumors, - Cowden Syndrome
8 Locations available
- Targeted Atomic Nano-Generators (Actinium-225-Labeled Humanized Anti-CD33 Monoclonal Antibody HuM195) in Patients With Advanced Myeloid Malignancies
Conditions: Leukemia - Myelodysplastic Syndrome
1 Location available
- Study of MLN4924 in Adult Patients With Nonhematologic Malignancies
Conditions: Advanced Nonhematologic Malignancies
3 Locations available
- Safety Study of Oral MGCD265 Administered Without Interruption to Subjects With Advanced Malignancies
Conditions: Advanced Malignancies
2 Locations available
- A Phase 1b Study of MDX-1106 in Subjects With Advanced or Recurrent Malignancies
Conditions: Metastatic Castration-resistant Prostrate Cancer (mCRPC) - Renal Cell Carcinoma (RCC) - Metastatic Melanoma (MEL) - Non-small Cell Lung Cancer (NSCLC)
10 Locations available
- Study of Advanced Bulky Malignancies With Spatially Fractioned Radiation Therapy
Conditions: Advanced Bulky Malignancies
1 Location available
- A Phase 1b Study of AMG 386 in Combination With Either Pegylated Liposomal Doxorubicin or Topotecan in Subjects With Advanced Recurrent Epithelial Ova
Conditions: Cancer - Carcinoma - Fallopian Tube Cancer - Gynecological Malignancies - Metastases - Oncology - Ovarian Cancer - Solid Tumors - Tumors
8 Locations available
- Pharmacodynamic Study of Axitinib in Patients With Advanced Solid Malignancies
Conditions: Solid Malignancies
1 Location available
- A Multiple-Ascending-Dose Study of the Safety and Tolerability of REGN421(SAR153192) in Patients With Advanced Solid Malignancies
Conditions: Advanced Solid Malignancies
3 Locations available
- A Safety Study Of A Monoclonal Antibody Against A5B1 Integrin In Solid Tumors
Conditions: Advanced Non-Hematologic Malignancies
4 Locations available
- Esophageal Sparing Intensity-modulated Radiation Therapy (IMRT) for Locally-Advanced Thoracic Malignancies
Conditions: Non Small Cell Lung Cancer - Small Cell Lung Cancer - Thymoma - Thymus Neoplasms
1 Location available
- Sirolimus and Cetuximab in Advanced Malignancies
Conditions: Advanced Cancer
1 Location available
- Busulfan-fludarabine Conditioning and T-cell Depleted Allogeneic Stem Cell Transplantation for Patients With Advanced Hematologic Malignancies
Conditions: Leukemia - Lymphoma - Myeloma
1 Location available
- Study of TAK-733 in Adult Patients With Advanced Nonhematologic Malignancies
Conditions: Advanced Non-hematologic Malignancies - Advanced Metastatic Melanoma
2 Locations available
- A Study of CDX-1401 in Patients With Malignancies Known to Express NY-ESO-1
Conditions: Advanced Malignancies
7 Locations available
- A Study of MGCD265 Given With Erlotinib or Docetaxel in Subjects With Advanced Malignancies or Non-Small Cell Lung Cancer
Conditions: Advanced Malignancies, Non-small Cell Lung Cancer
2 Locations available
- Study is Designed to Assess the Safety and Tolerability of AZD4547 at Increasing Doses in Patients With Advanced Tumours
Conditions: Cancer - Advanced Solid Malignancies
3 Locations available
- A Clinical Study Using MEDI-551 in Adult Subjects With Relapsed or Refractory Advanced B-Cell Malignancies
Conditions: B-cell Malignancies
6 Locations available
- Intensity Modulated Total Marrow Irradiation (IM-TMI) for Advanced Hematologic Malignancies
Conditions: Acute Myeloid Leukemia - Lymphoblastic Leukemia - Acute Leukemia - Non Hodgkins Lymphoma - Chronic Myeloid Leukemia
1 Location available
- Use of Hydralzaine and Valproic Acid in Advanced Solid Tumor Malignancies
Conditions: Lung Cancer
1 Location available
- A Dose Escalation Study in Adult Patients With Advanced Solid Malignancies
Conditions: Advanced Solid Tumors With FGFR1 Amplication, - Advanced Solid Tumors With FGFR2 Amplication, - Advanced Solid Tumors With FGFR3 Mutation
7 Locations available
- Dasatinib, Bevacizumab, Paclitaxel in Patients With Advanced Malignancies
Conditions: Advanced Cancer
1 Location available
- Study to Evaluate Safety, Tolerability, Maximum Tolerated Dose (MTD), Efficacy, and Pharmacokinetics (PKs) of CPI-613 Given Twice Weekly for Three Con
Conditions: Advanced Hematologic Malignancies
1 Location available
- MLN8237 in Adults With Nonhematological Malignancies, Followed by MLN8237 in Lung, Breast, Head and Neck or Gastroesophageal Malignancies
Conditions: Advanced Nonhematological Malignancies - Non-Small Cell Lung Cancer - Small Cell Lung Cancer - Metastatic Breast Cancer - Head and Neck Squamous Cell Carcinoma - Gastroesophageal Adenocarcinoma
3 Locations available
- Docetaxel and Sirolimus in Patients With Advanced Malignancies
Conditions: Advanced Cancer
1 Location available
- Dose Escalation Study of INK128 in Subjects With Advanced Cancer
Conditions: Advanced Solid Malignancies
3 Locations available
- Phase I Dose Escalation Trial Evaluating the Safety and Tolerability of AZD6244 and IMC-A12 in Subjects With Advanced Solid Malignancies
Conditions: Malignant Solid Tumour
1 Location available
- A Dose-escalation Study in Subjects With Advanced Malignancies
Conditions: Advanced Malignancies
2 Locations available
- Trial Of Cisplatin And KML-001 In Advanced Non-Small Cell Lung Cancer and Other Platinum Responsive Malignancies
Conditions: Advanced Non-Small Cell Lung Cancer - Platinum Responsive Malignancies
1 Location available
- ABT-348 as Monotherapy and in Combination With Azacitidine to Treat Advanced Hematologic Malignancies
Conditions: Acute Myelogenous Leukemia - Acute Lymphoblastic Leukemia - Chronic Myelogenous Leukemia - B-cell Chronic Lymphocytic Leukemia - Myelodysplasia
2 Locations available
- Nab-paclitaxel, Gemcitabine, and Bevacizumab in Advanced Malignancies
Conditions: Advanced Cancer
1 Location available
- 4'-Thio-araC (Thiarabine) in Advanced Hematologic Malignancies
Conditions: Leukemia
1 Location available
- Study of Orally Administered TAK-960 in Patients With Advanced Nonhematologic Malignancies
Conditions: Advanced Nonhematological Malignancies
2 Locations available
- Gemcitabine and Split-Dose Cisplatin Plus Everolimus (RAD001) in Patients With Advanced Solid Tumor Malignancies
Conditions: Bladder Cancer - Renal Pelvis Cancer - Ureter Cancer
1 Location available
- A Dose-escalation Study in Subjects With Advanced Malignancies
Conditions: Advanced Malignancies
2 Locations available
- A Study of TAK-441 in Adult Patients With Advanced Nonhematologic Malignancies
Conditions: Advanced Nonhematologic Malignancies - Carcinoma, Basal Cell
2 Locations available
- A Dose-Escalation and Pharmacokinetic Study of TG02 Citrate in Patients With Advanced Hematological Malignancies
Conditions: AML - ALL - CML in Blast Crisis - High-Risk MDS - Multiple Myeloma
5 Locations available
- A Study of BYL719 in Adult Patients With Advanced Solid Malignancies, Whose Tumors Have an Alteration of the PIK3CA Gene
Conditions: Advanced Solid Tumors - With an Alteration of the PIK3CA Gene
4 Locations available
- MK-2206, Paclitaxel and Trastuzumab in Treating Patients With HER2-overexpressing Solid Tumor Malignancies
Conditions: Advanced Solid Tumors - Tumors - Cancer
1 Location available
- Study of CA-18C3 in Subjects With Advanced Hematologic Malignancies
Conditions: Hematologic Malignancies
1 Location available
- ABT-888 in Combo of LDFWAR to Treat Patients With Advanced Solid Malignancies With Peritoneal Carcinomatosis
Conditions: Advanced Solid Tumor With Peritoneal Carcinomatosis
1 Location available
- A Study to Assess the Potential Effects of Rifampin on the Pharmacokinetics of Trabectedin in Patients With Advanced Malignancies
Conditions: Neoplasm Metastases
2 Locations available
- A Pharmacokinetic Study of Trabectedin in Patients With Advanced Malignancies and Hepatic Dysfunction
Conditions: Neoplasm Metastases - Hepatic Insufficiency
4 Locations available
- Study of an Investigational Drug, ASP3026, in Patients With Advanced Malignancies (Solid Tumors and B-Cell Lymphoma)
Conditions: Advanced Malignancies - B-Cell Lymphoma - Solid Tumor
2 Locations available
- Molecular Profiling and Targeted Therapy for Advanced Non-Small Cell Lung Cancer, Small Cell Lung Cancer, and Thymic Malignancies
Conditions: Carcinoma, Non-Small-Cell Lung - Carcinoma, Small Cell Lung - Carcinoma, Thymic
2 Locations available
- A Clinical Study of BBI608 Administered With Paclitaxel in Adult Patients With Advanced Malignancies
Conditions: Cancer
1 Location available
- Dose Escalation Study of INK128 in Combination With Paclitaxel, With/Without Trastuzumab, in Subjects With Advanced Solid Malignancies
Conditions: Breast Cancer
2 Locations available
- The First-in-human Phase I Trial of PU-H71 in Patients With Advanced Malignancies
Conditions: Metastatic Solid Tumor - Lymphoma
1 Location available
- Study of BMN 673, a PARP Inhibitor, in Patients With Advanced Hematological Malignancies
Conditions: Acute Myeloid Leukemia - Myelodysplastic Syndrome - Chronic Lymphocytic Leukemia - Mantle Cell Lymphoma
1 Location available
- Study of PWT33597 Mesylate in Subjects With Advanced Malignancies
Conditions: Malignancies
4 Locations available
- Phase 1 Study of Oral MLN9708 in Patients With Advanced Nonhematologic Malignancies or Lymphoma
Conditions: Lymphoma - Waldenstrom's Macroglobulinemia - Nonhematologic Malignancies
5 Locations available
- A Phase 1/2 Study of the Oral ALK/EGFR Inhibitor AP26113
Conditions: Advanced Malignancies - Carcinoma, Non-Small-Cell Lung - Anaplastic Large Cell Lymphoma - Diffuse Large Cell Lymphoma - Inflammatory Myofibroblastic Tumors
6 Locations available
- Lapatinib and Bortezomib in Patients With Advanced Malignancies
Conditions: Advanced Solid Tumors
1 Location available
- Erlotinib in Combination With Pralatrexate in Advanced Malignancies
Conditions: Advanced Cancers - Solid Tumors
1 Location available
- A Phase I Study of BKM120 and Everolimus in Advanced Solid Malignancies
Conditions: Solid Tumors
1 Location available
- A Phase 1 Study of IPI-145 in Patients With Advanced Hematologic Malignancies
Conditions: Hematologic Malignancy
2 Locations available
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