Your search returned 202 studies. (Get alerts for new studies):
- Sex, Aging and Antiretroviral Pharmacokinetics
Conditions: HIV Infections
1 Location available
- Pharmacokinetics of Low Molecular Weight and Unfractionated Heparin in Pregnancy
Conditions: Recurrent Pregnancy Loss, - Fetal Demise - Abortion, Habitual - Antiphospholipid Antibodies - Inherited Thrombophilia
1 Location available
- A Multicenter, Open-Label Study To Investigate The Safety And Pharmacokinetics Of Lacosamide In Children With Partial Seizures
Conditions: Epilepsy
14 Locations available
- A Study to Describe the Pharmacokinetics of Acyclovir in Premature Infants (PTN_Acyclo)
Conditions: Herpes Simplex Virus - Neonatal Sepsis
2 Locations available
- Effect of Antacids on the Pharmacokinetics of Raltegravir
Conditions: HIV Infections
1 Location available
- Study to Evaluate Safety, Tolerability, Maximum Tolerated Dose (MTD), Efficacy, and Pharmacokinetics (PKs) of CPI-613 Given Twice Weekly for Three Con
Conditions: Advanced Hematologic Malignancies
1 Location available
- Rivaroxaban Pharmacokinetics/Pharmacodynamics (PK/PD) Study in Pediatric Subjects
Conditions: Venous Thrombosis - Pediatrics
1 Location available
- Pharmacokinetics/Pharmacodynamics (PK/PD) of Fluconazole in Children on Extracorporeal Membrane Oxygenation (ECMO)
Conditions: Cardiopulmonary Arrest - Fungal Infection
1 Location available
- Tenofovir, Emtricitabine, Efavirenz and Atazanavir Pharmacokinetics in the Aging HIV-Infected Population
Conditions: Human Immunodeficiency Virus
1 Location available
- Study to Evaluate the Safety, Pharmacokinetics and Efficacy of Recombinant Factor VIII Fc Fusion Protein (rFVIIIFc) in Subjects With Severe Hemophilia
Conditions: Severe Hemophilia A
23 Locations available
- A Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IV PRM151 in Patients With Idiopathic Pulmonary Fibrosis (IPF)
Conditions: Idiopathic Pulmonary Fibrosis
2 Locations available
- Dose Escalation Study to Determine Safety, Pharmacokinetics, and Pharmacodynamics of Intravenous TKM-080301
Conditions: Cancer
3 Locations available
- A Study of the Safety and Pharmacokinetics of Escalating Doses of DSTP3086S in Patients With Metastatic Castration-Resistant Prostate Cancer
Conditions: Prostate Cancer
3 Locations available
- Safety, Tolerability and Pharmacokinetics of Iloperidone Depot in Schizophrenic Patients
Conditions: Schizophrenia
1 Location available
- Study to Assess the Safety, Tolerability, and Pharmacokinetics of AMP-224 in Patients With Advanced Cancer
Conditions: Cancer
3 Locations available
- Assessment of Pharmacokinetics of a Single Oral Dose of VIMOVO in Healthy Adult Volunteers
Conditions: Juvenile Idiopathic Arthritis
1 Location available
- A Study Evaluating the Safety, Tolerability, and Pharmacokinetics of GDC-0425 Administered With and Without Gemcitabine in Patients With Refractory So
Conditions: Solid Tumour
2 Locations available
- Study of the Safety and Pharmacokinetics of MPDL3280A Administered Intravenously As a Single Agent to Patients With Locally Advanced or Metastatic Sol
Conditions: Solid Cancers
4 Locations available
- Safety, Pharmacokinetics, and Efficacy of RA-18C3 in Subjects With Moderate to Severe Psoriasis
Conditions: Psoriasis
3 Locations available
- Safety, Pharmacodynamics (PD), Pharmacokinetics (PK) Study of SHP141 in 1A, 1B, or 2A Cutaneous T-Cell Lymphoma (CTCL)
Conditions: Lymphoma, T-Cell, Cutaneous
4 Locations available
- Safety and Pharmacokinetics of Ifetroban in Hepatorenal Syndrome Patients
Conditions: Hepatorenal Syndrome
11 Locations available
- A 2-Part Single Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2006
Conditions: Insomnia
1 Location available
- A 6 Week Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of GK1-399 in Type 2 Diabetes
Conditions: Type 2 Diabetes Mellitus
11 Locations available
- Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of TAP311 in Healthy Subjects and Dyslipidemic Patients
Conditions: Dyslipidemia - Healthy Volunteers
1 Location available
- Safety and Tolerability of AZD1208 and the Pharmacokinetics and Efficacy of AZD1208 in Acute Myelogenous Leukemia (AML) Patients
Conditions: Acute Myeloid Leukemia
2 Locations available
- Baseline Sexual Function, Cognitive Function, Body Composition and Muscle Parameters and Pharmacokinetics of Transdermal Testosterone Gel in Women Wit
Conditions: Panhypopituitarism
1 Location available
- Comparison of Iodine-124 (I-124) and Iodine-131 (I-131) Radiopharmacokinetics
Conditions: Thyroid Cancer
1 Location available
- A Study on the Pharmacokinetics and Safety of Valcyte (Valganciclovir) in Pediatric Heart Transplant Recipients Less Than 4 Months of Age
Conditions: Cytomegalovirus Infections, Heart Transplantation
4 Locations available
- Evaluation of Food Effect on Pharmacokinetics of GDC-0449
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
1 Location available
- Study to Assess Safety, Pharmacokinetics, and Efficacy of Oral CC-223 for Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma or Multiple Myelom
Conditions: Multiple Myeloma - Diffuse Large B-Cell Lymphoma - Glioblastoma Multiforme - Hepatocellular Carcinoma - Non-Small Cell Lung Cancer - Gastrointestinal Neuroendocrine Tumors of Non-Pancreatic Origin - Hormone Receptor-Positive Breast Cancer
8 Locations available
- A Study of the Safety and Pharmacokinetics of Escalating Doses of DCDT2980S in Patients With Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma and
Conditions: Chronic Lymphocytic Leukemia - Non-Hodgkin's Lymphoma
6 Locations available
- A Study Evaluating the Safety, Tolerability and Pharmacokinetics of GDC-0917 Administered to Patients With Refractory Solid Tumors or Lymphoma
Conditions: Solid Cancers
2 Locations available
- Pharmacokinetics/Pharmacodynamics Biomarker Study in Active Ulcerative Colitis Patients
Conditions: Colitis, Ulcerative
30 Locations available
- To Evaluate the Preliminary Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of CC-11050 in Subjects With Discoid Lupus Erythemat
Conditions: Cutaneous Lupus Erythematosus
19 Locations available
- Pharmacokinetics (PK) of Dalfampridine-ER 7.5 mg BID in Healthy Volunteers and Subjects With Mild or Moderate Renal Impairment
Conditions: Renal Insufficiency
1 Location available
- Comparative Pharmacokinetics of a Compounded 6-mercaptopurine Liquid Formulation Preparation and Tablets
Conditions: Acute Lymphoblastic Leukemia
1 Location available
- Safety and Pharmacokinetics of DMUC5754A Administered Intravenously to Patients With Platinum-Resistant Ovarian Cancer
Conditions: Ovarian Cancer
3 Locations available
- Safety and Pharmacokinetics of Treating Liver Cancer With Drug-Eluting Beads
Conditions: Neoplasm Metastases - Melanoma - Colorectal Neoplasms
1 Location available
- Pharmacokinetics/Pharmacodynamics of Albiglutide
Conditions: Diabetes Mellitus, Type 2
4 Locations available
- Safety, Pharmacokinetics and Pharmacodynamics of BKM120 Plus MEK162 in Selected Advanced Solid Tumor Patients
Conditions: Advanced Solid Tumors, - Selected Solid Tumors
3 Locations available
- A Study to Assess the Effect of Severe Hepatic Impairment on the Pharmacokinetics of Intravenous Conivaptan
Conditions: Liver Disease
2 Locations available
- An Open-Label Study to Assess the Pharmacokinetics and Safety of HALAVEN™ in Subjects With Cancer Who Also Have Impaired Renal Function
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
3 Locations available
- A Study of the Safety and Pharmacokinetics of JNJ-38518168 in Japanese and Caucasian Male Participants and the Effect of JNJ-38518168 on the Blood Lev
Conditions: Healthy Male Volunteer
1 Location available
- A Study to Assess the Efficacy, Safety and Pharmacokinetics of Intravenous Conivaptan (Vaprisol®) in Pediatric Subjects With Euvolemic or Hypervolemic
Conditions: Hyponatremia
4 Locations available
- Dose-Escalation Study With ETI-204Placebo-Controlled, Sequential Group, Single Dose, Dose-Escalation Study to Evaluate the Safety and Pharmacokinetics
Conditions: Healthy Volunteers
1 Location available
- The Pharmacokinetics of Azithromycin Prophylaxis for Cesarean Delivery
Conditions: Endometritis
1 Location available
- Study to Evaluate Pharmacokinetics, Food Effect, Safety and Efficacy of Oral Azacitidine
Conditions: Myelodysplastic Syndromes - Leukemia, Myelomonocytic, Chronic - Leukemia, Myeloid, Acute
6 Locations available
- Pharmacokinetics and Pharmacodynamics and Selected Antibiotics During Pregnancy
Conditions: Pregnancy
1 Location available
- Effect of Calcium on Tasigna Pharmacokinetics (PK) in Healthy Volunteers
Conditions: Healthy
1 Location available
- Safety & Pharmacokinetics Study Of Azacitidine (SC And Oral) In Subjects With MDS, CMML, AML, Lymphoma And Multiple Myeloma
Conditions: Acute Myeloid Leukemia - Myelodysplastic Syndromes - Lymphoma - Multiple Myeloma - Leukemia, Myelomonocytic, Chronic
4 Locations available
- A Study to Assess the Pharmacokinetics (Blood Levels) of TMC114 (Darunavir) Taken With Ritonavir and/or TMC125 (Etravirine) and TMC278 (Rilpivirine) i
Conditions: HIV - HIV Infections - Pregnancy
6 Locations available
- Pharmacokinetics of Citalopram in Patients With Short Bowel Syndrome
Conditions: Short Bowel Syndrome
1 Location available
- Cerebrospinal Fluid (CSF) Pharmacokinetics of Antimicrobials in Children
Conditions: Infections
1 Location available
- A Study Evaluating the Safety, Tolerability and Pharmacokinetics of GDC-0973 in Combination With GDC-0941 When Administered in Patients With Locally A
Conditions: Solid Cancers
4 Locations available
- Single Ascending Dose Safety, Tolerability and Pharmacokinetics Study of GLYX-13 in Normal Volunteers
Conditions: Healthy
1 Location available
- Cerebrospinal Fluid Pharmacokinetics of Daptomycin
Conditions: Meningitis
1 Location available
- A Dose-Escalation Study Designed to Evaluate the Tolerability, Safety, Pharmacokinetics (PK), and Efficacy of Chronic Topical Ocular Application of IN
Conditions: Glaucoma - Ocular Hypertension
1 Location available
- Safety and Pharmacokinetics of MMX Mesalamine in Children and Adolescents With Ulcerative Colitis
Conditions: Ulcerative Colitis
3 Locations available
- A Study of the Safety and Pharmacokinetics of MINT1526A, Administered Intravenously As a Single Agent and in Combination With Bevacizumab to Patients
Conditions: Solid Cancers
2 Locations available
- A Phase 2a Study To Evaluate The Pharmacokinetics, Safety, Efficacy, Tolerability, And Pharmacodynamics of Sotatercept (ACE-011) for the Correction of
Conditions: Anemia
2 Locations available
- A Study to Investigate Safety, Pharmacokinetics (PK) and Pharmacodynamics (PD) of BKM120 Plus GSK1120212 in Selected Advanced Solid Tumor Patients
Conditions: Advanced and Selected Solid Tumors
2 Locations available
- Clinical Trial of L-Grb-2 Antisense Oligonucleotide in CML, AML, ALL & MDS
Conditions: Safety and Pharmacokinetics of L-Grb-2 in Treating CML, AML, CLL and MDS
1 Location available
- A Study of the Effect of Food on the Pharmacokinetics of Single Dose RO5185426 And the Safety And Efficacy of Continuous Administration in Patients Wi
Conditions: Malignant Melanoma
2 Locations available
- A Study to Assess the Potential Effects of Rifampin on the Pharmacokinetics of Trabectedin in Patients With Advanced Malignancies
Conditions: Neoplasm Metastases
2 Locations available
- Effects of Denosumab on the Pharmacokinetics of Etanercept
Conditions: Postmenopausal Osteoporosis - Rheumatoid Arthritis
2 Locations available
- Aqueous Absorption and Pharmacokinetics of Besivance Versus VIGAMOX in Patients Undergoing Phacoemulsification
Conditions: Cataracts
1 Location available
- Pharmacokinetics, Pharmacodynamics and Safety Evaluation of SAR279356 in Intensive Care Unit Mechanically Ventilated Patients
Conditions: Infection Prophylaxis
14 Locations available
- Impact of Menstrual Cycle on Antiretroviral Pharmacokinetics in HIV-Infected Women
Conditions: HIV Infected
1 Location available
- Phase I Dose Escalation Study of the Safety and Pharmacokinetics of ME-143 Single Agent for Refractory Solid Tumors
Conditions: Solid Tumors
2 Locations available
- A Study of the Safety and Pharmacokinetics of AGS-22M6E in Subjects With Malignant Solid Tumors That Express Nectin-4
Conditions: Tumors - Medical Oncology - Neoplasms
2 Locations available
- Evaluation of Safety, Pharmacokinetics, and Efficacy of Proellex Administered Vaginally in Women With Uterine Fibroids
Conditions: Uterine Fibroids
2 Locations available
- Tolerability and Pharmacokinetics of Iloperidone in Adolescent Patients
Conditions: Safety and Tolerability of Iloperidone
2 Locations available
- Pilot Study of Exenatide Pharmacokinetics and Pharmacodynamics in Gestational Diabetes
Conditions: Gestational Diabetes
2 Locations available
- Voriconazole Pharmacokinetics in Children With Gastrointestinal Graft Versus Host Disease
Conditions: Graft Versus Host Disease - Stem Cell Transplantation
1 Location available
- The Pharmacokinetics of Dexmedetomidine in Children
Conditions: Sedation
1 Location available
- Study of the Pharmacokinetics of Daptomycin in Children With Renal Disease
Conditions: Chronic Kidney Disease - Bacterial Infection
1 Location available
- Oral Fluid, Plasma and Whole Pharmacokinetics and Stability Following Smoked Cannabis
Conditions: Cannabis Use - Drug Abuse
1 Location available
- Safety, Pharmacokinetics and Clinical Activity of Oral ON 01910.Na in Solid Tumors
Conditions: Solid Tumor
1 Location available
- Pharmacokinetics of Off Label Pediatric Medications
Conditions: Off Label Use of Medications in Pediatric Patients
1 Location available
- Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AMG 181.
Conditions: Ulcerative Colitis - Crohn's Disease
4 Locations available
- A Study Assessing The Pharmacokinetics, Pharmacodynamics, Safety And Tolerability Of Subcutaneous Bolus And Subcutaneous Infusion Of Cenderitide In Pa
Conditions: Heart Failure - HF - Chronic Heart Failure - CHF
1 Location available
- Safety and Pharmacokinetics of TT30 in Subjects With Paroxysmal Nocturnal Hemoglobinuria (PNH)
Conditions: Paroxysmal Nocturnal Hemoglobinuria (PNH)
3 Locations available
- A Pharmacokinetics Study of the Effects of GSK2118436 on Warfarin, the Effects of Ketoconazole and Gemfibrozil on GSK2118436, and the Effects of Repea
Conditions: Drug Interactions - BRAF - Cancer
4 Locations available
- Safety and Pharmacokinetics of Escalating Doses of DNIB0600A in Patients With Non-Small Cell Lung Cancer and Platinum Resistant Ovarian Cancer
Conditions: Non-Small Cell Lung Cancer, Ovarian Cancer
3 Locations available
- Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) Assessment of LIK066 in Healthy Subjects and in Patients With Type 2 Diabetes Me
Conditions: Type 2 Diabetes Mellitus (T2DM)
1 Location available
- Pharmacokinetics of Alglucosidase Alfa in Patients Aged 8-18 Years of Age
Conditions: Pompe Disease (Late-Onset) - Glycogen Storage Disease Type II (GSD II) - Glycogenesis 2 - Acid Maltase Deficiency
1 Location available
- Pharmacokinetics - Pharmacodynamic Study of HT-2157 in Healthy Subjects and in Patients With Major Depressive Disorder
Conditions: Healthy Volunteers (Part 1) - Major Depressive Disorder (Part 2)
1 Location available
- A Study to Evaluate The Pharmacokinetics Of Crizotinib (PF-02341066) In Subjects With Impaired Renal Function
Conditions: Renal Impairment
2 Locations available
- Imaging of Brain Receptors Using (11C)mGlu1
Conditions: Dosimetry - Pharmacokinetics
1 Location available
- Pharmacokinetics of Peginterferon Alfa-2b in Participants With Moderate and Severe Renal Impairment (P05655 AM2)
Conditions: Renal Insufficiency
2 Locations available
- Safety, Antiviral Activity, and Pharmacokinetics of GSK2336805 With Peginterferon and Ribavirin in Chronic Hepatitis C Subjects
Conditions: Hepatitis C, Chronic
4 Locations available
- A Clinical Trial to Evaluate the Pharmacokinetics of Testosterone Gel Using an Applicator
Conditions: Hypogonadal Males
1 Location available
- Safety, Tolerability, Pharmacokinetics, and Immunoregulatory Study of BMS-663513 in Subjects With Advanced and/or Metastatic Solid Tumors
Conditions: Cancer - Solid Tumors
4 Locations available
- Pharmacokinetics-based Mycophenolate Mofetil Dosing for GVHD Prevention
Conditions: Allogeneic Blood and Marrow Transplantation (BMT) - Graft Versus Host Disease
1 Location available
- Pharmacokinetics of Tasimelteon in Subjects With Renal Impairment and Matched Control Subjects With Relatively Normal Renal Function
Conditions: Renal Impairment
3 Locations available
- A Study To Compare Pharmacokinetics Of Dacomitinib Between Healthy Subjects And Subjects With Mild And Moderate Hepatic Impairment
Conditions: Healthy - Otherwise Healthy Volunteers With Mild or Moderate Hepatic Dysfunction
1 Location available
- Pharmacokinetics and Tolerability of Lu AA21004 in Child and Adolescent Patients With Depressive or Anxiety Disorder
Conditions: Depressive Disorder - Anxiety Disorder
1 Location available
- Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Clinical Effects of AMG 557 in Adults With Psoriasis
Conditions: Psoriasis
6 Locations available
- Evaluation of the Safety, Pharmacokinetics, and Pharmacodynamics of Multiple Doses of E2609 in Healthy Subjects
Conditions: Healthy
1 Location available
- A Study in Healthy Volunteers to Evaluate the Safety, Tolerability, and Pharmacokinetics Profiles of Single and Multiple Ascending Oral Doses of TG-23
Conditions: Healthy
1 Location available
- A Study of the Pharmacokinetics and Antiviral Activity of Dolutegravir in the Central Nervous System in HIV-1 Infected ART-naive Subjects
Conditions: Infection, Human Immunodeficiency Virus
1 Location available
- Study of the Effect of Renal Impairment on the Pharmacokinetics of Isavuconazole.
Conditions: Pharmacokinetics of Isavuconazole - Healthy Volunteers - Renal Impaired
1 Location available
- A Study to Assess the Effect of Timing of Food Intake on the Pharmacokinetics of Abiraterone Following Single-Dose Administration of Abiraterone Aceta
Conditions: Pharmacology
1 Location available
- Analyses of Human Samples Collected in Clinical Trials
Conditions: Pharmacokinetics
12 Locations available
- Pharmacokinetics of Low Dose Ketamine Infusion
Conditions: Sedation - Opioid Tolerance
1 Location available
- Effect of Calcium on Gleevec Pharmacokinetics (PK) in Healthy Volunteers
Conditions: Healthy
1 Location available
- A Phase 1, Dose Escalation Study of the Safety, Tolerability, and Pharmacokinetics of Intravenous Dimethane Sulfonate (DMS612) in Advanced Malignancie
Conditions: Renal Cell Carcinoma - Breast Cancer - Colon Cancer - Lung Cancer - Non-Hodgkin Lymphoma
3 Locations available
- Pharmacokinetics, Pharmacodynamics and Safety of Alogliptin in Children, Adolescents and Adults With Type 2 Diabetes Mellitus
Conditions: Diabetes Mellitus, Type 2
5 Locations available
- Safety, Tolerability and Pharmacokinetics of Single Dose Intravenous Moxifloxacin in Pediatric Patients
Conditions: Infections
5 Locations available
- Efficacy, Safety, Tolerability, Pharmacokinetics of Sotrastaurin-tacrolimus vs. Mycophenolic Acid-tacrolimus in de Novo Liver Transplant Patients
Conditions: Liver Transplantation
12 Locations available
- Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AMG 181 in Healthy Subjects and Subjects With Mild to Moderate Ulcerative Colitis
Conditions: Ulcerative Colitis
2 Locations available
- Safety and Pharmacokinetics Study of Human Monoclonal Antibody (FGI-101-1A6)
Conditions: Influenza
1 Location available
- Phase I Clinical Trial to Evaluate the Safety, Pharmacokinetics and Efficacy of CW002
Conditions: Healthy
1 Location available
- Safety, Efficacy and Pharmacokinetics of an Oral Iron Chelator Given for a Year to Pediatric Patients With Iron Overload
Conditions: Transfusional Iron Overload - Beta-Thalassemia
1 Location available
- Contraception and Menstrual Cycle Effect on Pharmacokinetics, Pharmacodynamics and Safety in Tenofovir Vaginal Gel Use
Conditions: HIV Prevention
2 Locations available
- Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
Conditions: Infection - Hypertension - Anesthesia - Pain - Reflux
10 Locations available
- Evaluation of Safety and Efficacy, Including Pharmacokinetics, of NNC 0129-0000-1003 When Administered for Treatment and Prophylaxis of Bleeding in Su
Conditions: Haemophilia A
33 Locations available
- Pharmacokinetics, Safety, and Tolerability of Subcutaneous GAMUNEX-C in Pediatric Subjects With Primary Immunodeficiency
Conditions: Primary Immunodeficiency
3 Locations available
- TAK-875 Glimepiride Drug-Interaction Study
Conditions: Pharmacokinetics
1 Location available
- BMS - Safety, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Dapagliflozin in Type 1 Diabetes
Conditions: Type 1 Diabetes Mellitus
12 Locations available
- Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of SUN13837 Injection in Adult Subjects With Acute Spinal Cord Injury (ASCI)
Conditions: Acute Spinal Cord Injury
11 Locations available
- A Study Evaluating the Safety, Tolerability, and Pharmacokinetics of GDC-0973 in Combination With GDC-0068 When Administered in Patients With Locally
Conditions: Neoplasms
2 Locations available
- Study in Healthy Volunteers to Assess the Pharmacokinetics of Midazolam Administered Alone and in Combination With Vandetanib
Conditions: Healthy Volunteers
1 Location available
- A Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of GSK525762 in Subjects With NUT Midline Carcinoma (NMC)
Conditions: Carcinoma, Midline
1 Location available
- Adiponectin Polymorphisms, Insulin Resistance, and Pharmacokinetics in Obesity
Conditions: Obesity
1 Location available
- An Assessment of Milk Thistle Pharmacokinetics and Drug Interactions
Conditions: Healthy
1 Location available
- Safety, Pharmacokinetics and Efficacy of an AT-III Concentrate.
Conditions: Antithrombin III Deficiency
2 Locations available
- Pharmacodynamics and Pharmacokinetics of Citalopram and Escitalopram
Conditions: Depression
1 Location available
- Pharmacokinetics and Safety Study of Azacitidine in Cancer Patients With and Without Impaired Renal Function
Conditions: MDS - AML - Solid Tumors - Multiple Myeloma - Non-Hodgkin's Lymphoma - Hodgkin's Disease
8 Locations available
- Pharmacokinetics and Safety of Panobinostat in Patients With Advanced Solid Tumors and Various Degrees of Hepatic Function
Conditions: Advanced Solid Tumors
1 Location available
- Pharmacokinetics, Safety, and Tolerability of Intravenous Posaconazole Solution Followed by Oral Posaconazole Suspension in Subjects at High Risk for
Conditions: Fungal Infection
7 Locations available
- Efficacy, Safety, Tolerability and Pharmacokinetics (PK) of Nilotinib (AMN107) in Pulmonary Arterial Hypertension (PAH)
Conditions: Pulmonary Arterial Hypertension
2 Locations available
- Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of Saxagliptin as Monotherapy in Pediatric Patients With Type 2 Diabetes
Conditions: Type 2 Diabetes
20 Locations available
- Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of GSK2126458 and GSK1120212 Combination Therapy in Subject
Conditions: Cancer
2 Locations available
- Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Properties of Oral AT-406 in Combination With Daunorubicin and Cytarabine in P
Conditions: Acute Myelogenous Leukemia (AML)
5 Locations available
- Evaluation of the Pharmacokinetics, Safety, and Tolerability of TPM XR as Adjunctive Therapy in Pediatric Subjects With Epilepsy
Conditions: Epilepsy
10 Locations available
- A Phase 1 Study Evaluating the Safety and Pharmacokinetics of ABT-199 in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia and Non-Hod
Conditions: Chronic Lymphocytic Leukemia - Non-Hodgkin's Lymphoma
4 Locations available
- Dose Ranging Pharmacokinetics and Pharmacodynamics Study With Mepolizumab in Asthma Patients With Elevated Eosinophils
Conditions: Asthma
1 Location available
- Safety, Pharmacokinetics and Pharmacodynamics of BPS804 in Osteogenesis Imperfecta
Conditions: Osteogenesis Imperfecta
2 Locations available
- Safety and Pharmacokinetics of Single Oral Doses of MBX-400 in Healthy Volunteers
Conditions: Healthy Adult Subjects
1 Location available
- An Immunogenicity and Pharmacokinetics (PK) Study of DAC HYP Prefilled Syringe in Relapsing Remitting Multiple Sclerosis (RRMS)
Conditions: Relapsing Remitting Multiple Sclerosis
7 Locations available
- Study to Assess the Pharmacokinetics of Cabozantinib (XL184) in Hepatic Impaired Adult Subjects
Conditions: Healthy - Hepatic Impairment
1 Location available
- Pharmacokinetics of Vancomycin for Inhalation in Cystic Fibrosis
Conditions: Cystic Fibrosis - Methicillin-resistant Staphylococcus Aureus
1 Location available
- Pharmacokinetics of BIA 9-1067 in Healthy Japanese and Caucasian Subjects
Conditions: Parkinson Disease
1 Location available
- Single-dose Iloperidone Pharmacokinetics in Patients With Mild or Moderate Liver Disease, Compared to Healthy Volunteers
Conditions: Hepatic Impairment
2 Locations available
- Study in Healthy Volunteers to Assess Effect of Omeprazole and Ranitidine on the Pharmacokinetics of Vandetanib
Conditions: Pharmacokinetic - Cmax - Tmax - Plasma AUC - Plasma [AUC(0-t)] - Plasma [AUC(0-672)] - (t1/2,λz)
1 Location available
- Study of the Effect of Repeat Doses of Isavuconazole on Cardiac Repolarization
Conditions: Pharmacokinetics of Isavuconazole - Healthy Volunteers
1 Location available
- Drug Interaction Study of Isavuconazole and Methadone
Conditions: Pharmacokinetics of Isavuconazole - Pharmacokinetics of Methadone - Healthy Volunteers
1 Location available
- A Study To Characterize The Pharmacokinetics Of Oxycodone In Healthy Volunteers
Conditions: Management of Moderate to Severe Pain
1 Location available
- Study to Evaluate Safety, Pharmacokinetics, and Preliminary Efficacy of CO-1686 in Previously Treated Mutant Epidermal Growth Factor Receptor (EGFR) N
Conditions: Locally Advanced or Metastatic Non-small Cell Lung Cancer.
2 Locations available
- Safety, Efficacy and Pharmacokinetics of OMS302 in Subjects Undergoing Intraocular Lens Replacement With Phacoemulsification
Conditions: Intraocular Lens Replacement
4 Locations available
- Pharmacokinetics and Safety of Ertapenem in the Postpartum Period
Conditions: Endometritis
1 Location available
- Study to Evaluate Panobinostat (DACi) Pharmacokinetics and Safety in Solid Tumors and Varying Renal Function
Conditions: Advanced Solid Tumors
1 Location available
- Pharmacokinetics of Tranexamic Acid (TXA) in Children Undergoing Repair of Congenital Heart Defects Utilizing Cardiopulmonary Bypass
Conditions: Congenital Heart Disease
2 Locations available
- Investigate Safety, Pharmacokinetics and Pharmacodynamics of GSK2118436 & GSK1120212
Conditions: Cancer
13 Locations available
- Study of the Pharmacokinetics and Pharmacodynamics of POSIPHEN® in Subjects With Amnestic Mild Cognitive Impairment
Conditions: Alzheimer's Disease - Amnestic Mild Cognitive Impairment
1 Location available
- A Study Evaluating the Safety, Tolerability, and Pharmacokinetics of GDC-0623 in Patients With Locally Advanced or Metastatic Solid Tumors
Conditions: Solid Cancers
3 Locations available
- A First in Man Study to Determine the Safety at Various Dose Levels of AGS-16M8F in Advanced Kidney Cancer
Conditions: Renal Cell Carcinoma - Pharmacokinetics of AGS-16M8F
3 Locations available
- Pharmacokinetics and Tolerability Study of Tapentadol for Postsurgical Pain in Children and Adolescents
Conditions: Pain, Postoperative - Postoperative Pain
3 Locations available
- Effect of Weight and/or Obesity on Sulfamethoxazole and Trimethoprim Concentrations
Conditions: Obesity - Pharmacokinetics - MRSA - Tuberculosis - PCP
1 Location available
- A Randomized, Double-blind, Placebo-controlled, Sequential Ascending, Single-dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Ph
Conditions: Alzheimer's Disease
1 Location available
- To Evaluate the Safety, Activity and Pharmacokinetics of Marqibo in Children and Adolescents With Refractory Cancer
Conditions: Sarcoma - Neuroblastoma - Wilms Tumor - Leukemia - Lymphoma - Brain Tumors
1 Location available
- Gemcitabine Pharmacokinetics
Conditions: Pancreatic Cancer
1 Location available
- Safety, Pharmacokinetics (PK), and Efficacy of Buprenorphine Transdermal System (BTDS) in Children
Conditions: Pain
1 Location available
- Phase I Trial to Evaluate the Safety, Activity and Pharmacokinetics of Marqibo(Registered Trademark) (Vincristine Sulfate Liposomes Injection) in Chil
Conditions: Sarcoma - Neuroblastoma - Wilms Tumor - Leukemia - Lymphoma - Brain Tumors
1 Location available
- Effects of Gastric pH on the Pharmacokinetics of Dasatinib
Conditions: Healthy
1 Location available
- Pharmacokinetics of Boceprevir in Pediatric Subjects With Chronic Hepatitis C Genotype 1 (SCH503034-P07614 AM4)
Conditions: Hepatitis C, Chronic
2 Locations available
- Multiple-Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ONO-2952 in Healthy Adult Subjects
Conditions: Healthy
1 Location available
- Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Response of Vasomera (PB1046) Injection Following a Single Subcutaneous Dose in Subjects W
Conditions: Essential Hypertension
4 Locations available
- A Study to Look at How a Single Oral Dose of 14C-OSI-906 is Absorbed, Broken Down and Eliminated in the Body
Conditions: Advanced Solid Tumors - Pharmacokinetics of 14C-OSI-906
1 Location available
- Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Study Of PF-04427429 In Healthy Women Volunteers
Conditions: Pain - Migraine Disorders
3 Locations available
- A Study of the Pharmacokinetics and Pharmacodynamics of MK4618 in Women With Overactive Bladder (MK-4618-004)
Conditions: Overactive Bladder - Overactive Urinary Bladder
1 Location available
- Pharmacokinetics Of Tigecycline In Morbidly Obese Subjects
Conditions: Obesity
1 Location available
- Study in Healthy Volunteers to Assess the Pharmacokinetics (PK) of Digoxin Administered Alone and in Combination With Vandetanib
Conditions: Healthy Volunteers
1 Location available
- A Two-Part, Single-Dose Study of the Pharmacokinetics of MK-8931 in Subjects With Renal Insufficiency (MK-8931-009 [P08535])
Conditions: Alzheimer's Disease
2 Locations available
- Study Assessing Safety, Pharmacokinetics and Efficacy of CC-223 With Either Erlotinib or Oral Azacitidine in Advanced Non-Small Cell Lung Cancer
Conditions: Carcinoma, Non-Small-Cell Lung - Non-Small Cell Lung Cancer
1 Location available
- Pharmacokinetics Study of ALO-02 and OxyContin
Conditions: Management of Moderate to Severe Pain
1 Location available
- Prophylactic Use of Enoxaparin in Morbidly Obese Adolescents During Bariatric Surgery
Conditions: Focus of Study: Pharmacokinetics of Enoxaparin in Obese Children
1 Location available
- Study to Assess the Safety, Tolerability, Pharmacokinetics and Antiviral Activity of ABT-267 in HCV Infected Subjects
Conditions: HCV Infection
4 Locations available
- Pharmacokinetics, Safety, and Tolerability of TR-701 Free Acid (FA) in Elderly Subjects
Conditions: Healthy Subjects
1 Location available
- Study in Healthy Volunteers to Investigate the Effects of Quinidine on the Pharmacokinetics of NKTR-118
Conditions: Drug Induced Constipation
1 Location available
- Study in Healthy Volunteers to Investigate the Effects of Rifampin on the Pharmacokinetics of NKTR-118
Conditions: Drug Induced Constipation
1 Location available
- Study to Assess Food Effect on Pharmacokinetics of Entinostat in Subjects With Breast Cancer or Non-Small Cell Lung Cancer
Conditions: Lung Cancer - Non Small Cell Lung Cancer (NSCLC) - Breast Cancer - ER+ Breast Cancer
2 Locations available
- Pharmacokinetics of LCQ908 in Patients With Hepatic Impairment
Conditions: Hepatic Impairment
2 Locations available
- A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ACHN-975 in Healthy Volunteers
Conditions: Healthy Volunteer
1 Location available
- Study To Assess The Safety, Pharmacokinetics, And Evaluate The Response To Anidulafungin When Treating Children With Invasive Candidiasis
Conditions: Candidemia - Candidiasis
6 Locations available
- An Open Label Study to Describe the Pharmacokinetics of Daptomycin in Infants
Conditions: Sepsis
1 Location available
- Dose-Finding Study 9cUAB30 in Normal Volunteers
Conditions: Pharmacokinetics - Adverse Events
2 Locations available
- Safety, Pharmacokinetics and Pharmacodynamics of BEZ235 Plus MEK162 in Selected Advanced Solid Tumor Patients
Conditions: Unspecified Adult Solid Tumor, Protocol Specific - Solid Tumor
3 Locations available
- A Study on the Effect of Food on the Pharmacokinetics of RO5428029 in Healthy Volunteers
Conditions: Healthy Volunteer
1 Location available
- Safety and Pharmacokinetics of Dapivirine/Maraviroc Vaginal Ring
Conditions: HIV Infections
3 Locations available
- A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Etravirine Administered in Combination With Other Antiretroviral Agents in Antir
Conditions: Human Immunodeficiency Virus (HIV) Infection
9 Locations available
- Population Pharmacokinetics of Prolonged Infusion Meropenem in Cystic Fibrosis (CF) Children
Conditions: Cystic Fibrosis - Pneumonia - Pseudomonas Aeruginosa Infection
3 Locations available
- Safety and Pharmacokinetics of Single and Multiple Dose Rifampin in Infants
Conditions: Infection
1 Location available
- A Study to Assess Pharmacokinetics of Preladenant in Participants With Chronic Hepatic Impairment (P06513)
Conditions: Chronic Hepatic Impairment
1 Location available
- Effect of Haemodialysis on the Pharmacokinetics of Ezogabine/Retigabine and Its N-acetyl Metabolite
Conditions: Epilepsy
1 Location available
- Multiple-Dose Pharmacokinetics (PK), and Pharmacodynamic (PD) Effect of NSI-189 Phosphate in Depression Patient Subjects
Conditions: Depression
1 Location available
- Single Cohort, 2-Period Study to Assess Pharmacokinetics of Metformin Alone and in Combination With Ranolazine 500 mg
Conditions: Type 2 Diabetes Mellitus
1 Location available
- A Phase I Study to Assess the Pharmacokinetics of Metformin When Administered Alone and in Combination With Vandetanib
Conditions: Healthy
1 Location available
- A Drug-Drug Interaction Study to Evaluate the Effect of Rifampin on the Pharmacokinetics of Apremilast
Conditions: Healthy
1 Location available
- Genetic Influence on Statin Pharmacokinetics
Conditions: Hyperlipidemia - Hypercholesterolemia - Dyslipidemia
1 Location available
- To Evaluate the Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of Calcipotriene 0.005%, Applied Under Maximal Use Conditions in 12-16 Yea
Conditions: Psoriasis
3 Locations available
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