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City:		Tacoma
State:		WA
Zip Code:		98405
Study summary:		Click image to enlarge We hope the EMPHASIS study will help us discover whether the investigational medication has any effect on the breathing of people with emphysema, on how efficiently their lungs work and on other effects of the disease, such as coughing. Inclusion Criteria: Be male or female, 40-65 yrs old, inclusive Rating of greater than or equal to 1 on the Goddard scale in assessment of emphysema severity by HRCT At least 1 documented COPD exacerbation within the past year but not within 8 weeks of study randomization Current or former smokers with a cigarette smoking history of at least 20 pack-years (or equivalent) and whose smoking status has not changed 60 days prior to screening Exclusion Criteria Patients with asthma, active tuberculosis or bronchieectasis A respiratory tract infection within 30 days prior to the screening visit Any malignancy within 30 days prior to the screening visit Any malignancy within the last 5 years with the exception of non-melanomatous skin cancer Uncontrolled cardiovascular, endocrine, blood or nervous system disorders Uncontrolled condition with COPD exacerbation of level 2 or 3 in the 8-week period prior to randomization Systemic use of corticosteroids or other immunosuppressive agents within 30 days of the screening visit Subjects taking anticoagulants
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Clinical trials are medical research studies designed to test the safety and/or effectiveness of new investigational drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials or take the Participation Quiz to find out if you are a good candidate for clinical trial participation.

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