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Alopecia Areata Registry and Immunogenetic Mechanisms

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City:   Minneapolis
State:   Minnesota
Zip Code:   55455
Conditions:   Alopecia Areata
Purpose:   The goals of this study are to understand the genetic control of autoimmunity in alopecia areata (AA), to better understand the complex biology of the cycling hair follicle, and to use this knowledge to devise safe and effective treatments for this common disease.
Study Summary:   The purpose of this registry is to collect patient epidemiology data as well as to provide samples that can be used for understanding the pathogenesis of AA, especially related to its genetic basis as a complex trait. There are three ways one can assess which genes are important: association studies in unrelated individuals, identify by descent in sib-pairs, and linkage or transmission by descent in multiplex families.
Criteria:   Inclusion Criteria: - All patients with AA, children and adults, who have been diagnosed by a dermatologist, who is an expert in the field of alopecia. Subtypes that are allowable are alopecia universalis, alopecia totalis, patchy persistent alopecia or transient mild alopecia. - Family members, related by blood, of these patients (preferably sib-pairs plus parents and multiplex families). - Age matched controls from spouses or clinic patients Exclusion Criteria: - A person under the age of 18 years not accompanied by parent or guardian. - A person who is unable to comprehend the informed consent and sign the consent form.
NCT ID:   NCT00177073
Primary Contact:   Principal Investigator
Maria Hordinsky, MD
University of Minnesota - Clinical and Translational Science Institute

Maria Hordinsky, MD
Phone: 612-625-1493
Email: hordi001@umn.edu
Backup Contact:   N/A
Location Contact:   Minneapolis, Minnesota 55455
United States

Maria Hordinsky, MD
Phone: 612-625-1493
Email: hordi001@umn.edu

Site Status: Recruiting

Data Source:   ClinicalTrials.gov
Date Processed:   June 19, 2013
Modifications to this listing:   Only selected fields are shown, please use the link below to view all information about this clinical trial.
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