A Longitudinal Study of Plasma EBV DNA in Nasopharyngeal Carcinoma From Both Endemic and Non-Endemic Patient Populations

Conditions:		Mouth Cancer - Lip Cancer - Throat Cancer - Lip Neoplasms - Head and Neck Cancers
Purpose:		1. To determine the prognostic implication of plasma Epstein-Bar Virus (EBV) DNA concentrations, as measured by quantitative polymerase chain reaction (PCR) in patients with nasopharyngeal carcinoma (NPC). 2. To relate pretreatment plasma EBV DNA concentration to WHO classification of these tumors both in endemic and non-endemic areas. 3. To determine whether pretreatment plasma EBV DNA can serve as a prognostic factor for both endemic and non-endemic patient populations.
Study Summary:
Criteria:		Inclusion Criteria: - Having a new diagnosis of Nasopharyngeal carcinoma. - Being treated with either radiotherapy or chemoradiotherapy for this condition. Exclusion Criteria: - Age <18 since NPC is a very rare condition in this age group and may have a different biological behavior - Patients who are unable to provide informed consents for themselves.
NCT ID:		NCT00186433
Primary Contact:		Principal Investigator Quynh-Thu Le Stanford University Quynh-Thu Le Phone: (650) 498-6184 Email: qle@stanford.edu
Backup Contact:		N/A
Location Contact:		Stanford, California 94305 United States Quynh-Thu Le Phone: 650-498-6184 Email: qle@stanford.edu Site Status: Recruiting

Data Source:		ClinicalTrials.gov
Date Processed:		May 22, 2013
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