View Clinical Trial (Medical Research Study)
Evaluation of the Natural History of Patients With Tumors of the Central Nervous System
| City: |
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Bethesda |
| State: |
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Maryland |
| Zip Code: |
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20892 |
| Conditions: |
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Brain and Central Nervous System Tumors - Chordoma - Neuroblastoma |
| Purpose: |
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RATIONALE: Gathering information about patients with central nervous system tumors over time
may help doctors learn more about the disease and find better methods of treatment and
on-going care.
PURPOSE: This natural history study is collecting disease-related health information over
time from patients with central nervous system tumors being evaluated at the National
Institutes of Health.
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| Study Summary: |
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OBJECTIVES:
- Evaluate patients with CNS tumors who are probable future candidates for NCI phase I
and II protocols.
- Follow patients with CNS tumors that are representative of important scientific and/or
clinical principles.
- Attain a steady flow of patients with CNS tumors at the NIH, which will help to educate
nurses, medical residents, clinical fellows, and others in management and care of this
subgroup of cancer patients.
OUTLINE: Patients receive an initial evaluation by the NCI Neuro-Oncology Branch at the NIH
Clinical Center. Patients may choose to end their participation on the study after the
initial evaluation or may continue being evaluated at NIH. Generally, patients living in
close proximity to the NIH are followed at NIH every 3-6 months. Patients living at a
distance from NIH resume standard care with their local physician, but either they are
followed periodically at NIH (e.g., if disease progression occurs) or they (and/or their
physician) are contacted by the Neuro-Oncology Branch at least every 6 months to generally
follow the natural history of the disease and patient outcome.
Patients may undergo any or all of the following procedures at initial or follow-up
evaluations: MRI or CT scan, PET scan, blood tests, neurologic exam, and physical exam and
history.
PROJECTED ACCRUAL: A total of 3,000 patients will be accrued for this study.
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| Criteria: |
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DISEASE CHARACTERISTICS:
- Patients with CNS tumors who meet any of the following criteria:
- Potential candidate for a future NIH Neuro-Oncology Branch (NOB) protocol
- Tumor is of particular interest to the NOB because it poses important clinical
and/or scientific questions or sheds light on important aspects of the disease
- Tumor would offer an important educational benefit to neuro-oncology trainees
and staff
- Must not be immediately eligible for another ongoing NOB protocol
PATIENT CHARACTERISTICS:
Age
- 12 months and over
Performance status
- Not specified
Life expectancy
- Not specified
Hematopoietic
- Not specified
Hepatic
- Not specified
Renal
- Not specified
PRIOR CONCURRENT THERAPY:
Biologic therapy
- Not specified
Chemotherapy
- Not specified
Endocrine therapy
- Not specified
Radiotherapy
- Not specified
Surgery
- Not specified
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| NCT ID: |
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NCT00458640 |
| Primary Contact: |
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Study Chair
Howard A. Fine, MD
NCI - Neuro-Oncology Branch
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| Backup Contact: |
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N/A |
| Location Contact: |
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Bethesda, Maryland 20892
United States
Patient Recruitment
Phone: 888-NCI-1937
Site Status: Recruiting |
| Data Source: |
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ClinicalTrials.gov |
| Date Processed: |
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May 18, 2013 |
| Modifications to this listing: |
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