View Clinical Trial (Medical Research Study)
Ascertainment of Peripheral Blood or Saliva Samples for Genetic Epidemiology Studies of Familial Cancers
| City: |
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New York |
| State: |
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New York |
| Zip Code: |
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10065 |
| Conditions: |
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Breast Neoplasms - Ovarian Neoplasms - Colonic Neoplasms - Prostatic Neoplasms - Uterine Cervical Neoplasms - Leukemia - Lymphoma, Non-Hodgkin |
| Purpose: |
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The purpose of this study is to better understand the genetic causes of cancer and the
inherited tendency to develop cancer. To accomplish this, blood specimens and/or saliva
samples and/or tumor and normal tissue blocks from patients and families of patients with
cancer will be collected. Blood specimens will be frozen and stored for analysis at a later
date. Tumor tissue and normal tissue will be stored for analysis at a later date. In order
to perform this study, patients and members of their families will be asked to provide blood
samples and/or saliva samples. Individuals will be asked to provide a history of cancer in
their relatives at the time the blood sample is given. No relatives will be contacted before
they have been asked by a family member if they wish to participate in this study.
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| Study Summary: |
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Patients can provide either a blood or saliva sample for the protocol. For blood samples,
two tubes of blood (approximately 20 cc) will be drawn from the patient, utilizing a sterile
technique. The tubes will be rocked so as to mix the blood with the additive (EDTA) in the
tubes. For saliva samples, approximately 2-4 ml of saliva will be collected in specialized
Oragene DNA Self-Collection Kit tubes.
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| Criteria: |
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Inclusion Criteria:
- Patients accepted for referral to the Cancer Family Clinic of the Department of
Medicine at Memorial Sloan-Kettering Cancer Center are eligible for participation in
this study. Such patients should have a history of cancers of the breast, ovary,
colon, prostate, uterus, non-Hodgkin's lymphoma, leukemia, soft tissue sarcoma,
endocrine neoplasms, or other malignancies presenting in first degree relatives or in
successive generations as part of a suspected cancer family syndrome.
- Family members of probands including parents, sisters, brothers, half-brothers and
sisters, sons, daughters, grandparents, as well as aunts and uncles are also
eligible.
- This study involves research which presents no greater than minimal risk to children.
The assent of any minor should be obtained before the patient is entered into this
study.
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| NCT ID: |
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NCT00579163 |
| Primary Contact: |
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Principal Investigator
Kenneth Offit, MD
Memorial Sloan-Kettering Cancer Center
Kenneth Offit, MD
Phone: 646-888-4050
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| Backup Contact: |
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N/A |
| Location Contact: |
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New York, New York 10065
United States
There is no listed contact information for this specific location.
Site Status: Recruiting |
| Data Source: |
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ClinicalTrials.gov |
| Date Processed: |
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May 18, 2013 |
| Modifications to this listing: |
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