View Clinical Trial (Medical Research Study)
Early Detection and Treatment of Esophageal Injury After Catheter Ablation for Atrial Fibrillation
| City: |
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Oklahoma City |
| State: |
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Oklahoma |
| Zip Code: |
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73104 |
| Conditions: |
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Atrial Fibrillation |
| Purpose: |
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The purpose of this study is to prospectively follow the next 200 patients who undergo
catheter ablation of atrial fibrillation for symptoms and signs of esophageal injury.
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| Study Summary: |
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The purpose of this study is to prospectively follow the next 200 patients who undergo
catheter ablation of atrial fibrillation and endoscopy. If any signs of esophageal injury
are seen on endoscopy the patients will be treated with omeprazole and sucralfate and they
will have repeat endoscopy in two weeks. Patients who do not have any esophageal injury
will be contacted by telephone in two weeks to be assessed for GI symptoms.
Specific Aims: The specific aims of the study are to:
1. Assess the incidence of visible transmural esophageal injury following extensive
ablation in the posterior left atrium as measured by endoscopy1
2. Assess whether early detection of esophageal injury by endoscopy and treatment will
prevent development of more serious injury such as left atrial-esophageal fistula
3. Identify predictors of esophageal injury. In particular, to assess if esophageal
temperature rises during ablation correlate with development of esophageal injury and
if the absence of esophageal temperature rise during ablation correlate with the
absence of esophageal injury.
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| Criteria: |
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Inclusion Criteria:
- 18-80 years
- Scheduled to have catheter ablation of atrial fibrillation or left atrial
macroreentrant tachycardia.
Exclusion Criteria:
- Contraindication to endoscopy
- Pregnancy
- Prisoners
- Inability or unwillingness to give informed consent
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| NCT ID: |
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NCT00584922 |
| Primary Contact: |
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Principal Investigator
Karen Beckman, MD
University of Oklahoma
Karen Beckman, MD
Phone: 405-271-9696 ext. 37536
Email: Karen-Beckman@ouhsc.edu
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| Backup Contact: |
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N/A |
| Location Contact: |
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Oklahoma City, Oklahoma 73104
United States
There is no listed contact information for this specific location.
Site Status: Recruiting |
| Data Source: |
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ClinicalTrials.gov |
| Date Processed: |
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May 23, 2013 |
| Modifications to this listing: |
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