View Clinical Trial (Medical Research Study)
Diagnostic Evaluation of Obscure Gastrointestinal Bleeding
| City: |
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Boston |
| State: |
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Massachusetts |
| Zip Code: |
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02115 |
| Conditions: |
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Obscure Gastrointestinal Bleeding |
| Purpose: |
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Up to 5% of patients with recurrent gastrointestinal (GI) bleeding remain undiagnosed by EGD
and colonoscopy, the presumed source of bleeding in these patients being the small
intestine. These patients fall under the category of "obscure gastrointestinal bleeding,"
and frequently require an extensive diagnostic work-up. For these reasons, most patients who
present with obscure or occult gastrointestinal bleeding typically undergo multiple
endoscopic evaluations, including capsule endoscopy and various radiologic imaging studies,
including enteroclysis, small bowel series, CT scan, angiography, and radionuclide scan.
Recently, many centers (included the Brigham and Women's Hospital) have begun using capsule
endoscopy and CT enterography (CTE) for evaluation of suspected small bowel pathology. This
is an observational study enrolling patients referred to the Brigham and Women's Hospital
for obscure gastrointestinal bleeding designed to compare the diagnostic yield of various
diagnostic modalities, in particular capsule endoscopy and CT enterography in the evaluation
of obscure gastrointestinal bleeding.
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| Study Summary: |
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| Criteria: |
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Inclusion Criteria:
- Anemia, hematochezia, melena, Hematemesis, heme positive stool with negative
EGD+/-colonoscopy
Exclusion Criteria:
- Under the age of 18
- Unable to give consent
- IV Contrast Allergy (excluded from CT)
- Renal insufficiency (excluded from CT)
- Unable to swallow (excluded from capsule)
- Small bowel obstruction or stricturing disease (excluded from capsule)
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| NCT ID: |
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NCT00593021 |
| Primary Contact: |
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Principal Investigator
John R Saltzman, MD
Brigham and Women's Hospital
Jaya R Agrawal, MD, MPH
Phone: 617-525-8763
Email: jagrawal@partners.org
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| Backup Contact: |
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Email: jsaltzman@partners.org
John R Saltzman, MD
Phone: 617-525-8763
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| Location Contact: |
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Boston, Massachusetts 02115
United States
Jaya R Agrawal, MD, MPH
Phone: 617-525-8763
Email: jagrawal@partners.org
Site Status: Recruiting |
| Data Source: |
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ClinicalTrials.gov |
| Date Processed: |
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May 19, 2013 |
| Modifications to this listing: |
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