View Clinical Trial (Medical Research Study)
A Pilot Study to Investigate Germ-Line MEN1 and SDHD Gene Mutation in Familial Cases of Carcinoid Cancer
| City: |
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Piscataway |
| State: |
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New Jersey |
| Zip Code: |
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08854 |
| Conditions: |
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Carcinoid Neuroendocrine Cancer |
| Purpose: |
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There is a high incidence among the first degree relatives of the carcinoid patients,
indicating the involvement of genetic components in its initiation and pathogenesis.
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| Study Summary: |
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This proposed pilot study will conduct detailed interviews into the medical, environmental,
and family histories and to collect blood specimen to obtain DNA. The Blood specimen and
DNA will be processed by the Rutgers University Cell and DNA Repository (RUCDR) to rule out
Familial Multiple Endocrine Neoplasia (MEN 1), and succinate dehydrogenase complex, subunit
D (SDHD), gene inactivation thought to be associated with different types of carcinoid
cancer.
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| Criteria: |
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Inclusion Criteria:
1. Over the age of 18 years
2. More than one ,member of a family with a history of biopsy confirmed carcinoid tumor
3. English speaking
4. Mentally and emotionally capable of answering questions
5. Willing and available for study participation
6. At least one other family member with carcinoid tumor
Exclusion Criteria:
1. If you are under the age of 18 years,
2. If you are unable to understand or unable to provide informed consent,
3. If you have a psychological condition (i.e. depression, anxiety disorder, substance
abuse, etc.) which might cause you significant problems in dealing with test results.
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| NCT ID: |
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NCT00672269 |
| Primary Contact: |
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Principal Investigator
Nancy Gardner, PhD
Rutgers University
Nancy Gardner, PhD
Phone: 813-731-0894
Email: gardnern@rutgers.edu
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| Backup Contact: |
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Email: Shao@Biology.Rutgers.Edu
Changshun Shao, PhD
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| Location Contact: |
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Piscataway, New Jersey 08854
United States
Changshun Shao, PhD
Phone: 732-445-5406
Email: shao@biology.rutgers.edu
Site Status: Recruiting |
| Data Source: |
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ClinicalTrials.gov |
| Date Processed: |
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June 19, 2013 |
| Modifications to this listing: |
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