View Clinical Trial (Medical Research Study)
Phase I-II Trial of Hypofractionated Conformal Proton Beam Radiation Therapy for Favorable-risk Prostate Cancer
| City: |
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Loma Linda |
| State: |
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California |
| Zip Code: |
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92354 |
| Conditions: |
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Prostate Cancer |
| Purpose: |
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The purpose of this study is to determine hypofractionated conformal proton beam radiation
therapy of prostate cancer can achieve similar treatment benefits as our current
institutional standard with conventional fractionation.
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| Study Summary: |
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Radiation therapy has a long and established role in the curative treatment of
organ-confined prostate cancer. However, the optimal radiation dose and treatment schedule
remain unknown. The use of hypofractionation has a long and generally successful history in
conformal proton beam therapy. Several reports detailing the efficacy and safety of
hypofractionated conformal radiation therapy (with x-rays) of prostate cancer can be found
in the literature. Hypofractionated conformal proton beam radiation therapy has become our
institutional routine for the treatment of numerous solid tumors. The purpose of this study
is to determine if a shortened overall treatment schedule will result in equivalent tumor
control rates and no increased side effects as compared to our current institutional
standard treatment of an equivalent dose given over a longer period of time.
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| Criteria: |
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Inclusion Criteria:
- Histologically confirmed adenocarcinoma within 180 days of registration
- History & Physical Exam, including DRE, within 8 wks prior to registration
- Histologic evaluation of prostate biopsies at LLUMC, with Gleason score
assignment
- Clinical stage T1-T2C
- PSA less than 10 ng.ml within 180 days prior to registration
Exclusion Criteria:
- Prior or concurrent invasive malignancy
- Evidence of distant metastasis
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| NCT ID: |
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NCT00831623 |
| Primary Contact: |
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Principal Investigator
Jerry D Slater, MD
Loma Linda University Medical Center Dept. of Radiation Medicine
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| Backup Contact: |
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N/A |
| Location Contact: |
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Loma Linda, California 92354
United States
Jerry D Slater, MD
Phone: 909-558-4258
Email: jdslater@dominion.llumc.edu
Site Status: Recruiting |
| Data Source: |
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ClinicalTrials.gov |
| Date Processed: |
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May 20, 2013 |
| Modifications to this listing: |
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