Effect of Diet-induced Weight Loss on HIV-associated Metabolic Syndrome

Conditions:		HIV (Human Immunodeficiency Virus) - Metabolic Syndrome - HIV Infections
Purpose:		Obese HIV-positive women with Metabolic Syndrome (HIV-MS) and obese HIV-negative women with Metabolic Syndrome will be studied before and after achieving moderate (6%-8%) diet-induced weight loss. The investigators hypothesize that health markers will improve in both groups but that the improvement will be blunted in the women with HIV-MS.
Study Summary:
Criteria:		Inclusion Criteria: - Sedentary - Obese - Have either dyslipidemia (HDL < 50 or triglycerides > 150), waist circumference > 88cm, and impaired glucose tolerance or homeostasis model assessment value of > 3 - Subjects with HIV-MS must have been receiving HAART for > 6 months Exclusion Criteria: - Medication changes in the last 3 months - Diabetes mellitus - Medical problems that in the opinion of the principal investigator may interfere with patient safety - Substance abuse
NCT ID:		NCT00857298
Primary Contact:		Principal Investigator Dominic Reeds, MD Washington University School of Medicine Sherry Lassa-Claxton Phone: 314 362-7637 Email: lassa-claxton@WUSTL.EDU
Backup Contact:		N/A
Location Contact:		Saint Louis, Missouri 63110 United States Sherry Lassa-Claxton Phone: 314-362-7637 Email: lassa-claxton@WUSTL.EDU Site Status: Recruiting

Data Source:		ClinicalTrials.gov
Date Processed:		June 19, 2013
Modifications to this listing:		Only selected fields are shown, please use the link below to view all information about this clinical trial.
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