View Clinical Trial (Medical Research Study)
Semantic Memory, Financial Capacity and Brain Perfusion in MCI
| City: |
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Birmingham |
| State: |
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Alabama |
| Zip Code: |
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35233 |
| Conditions: |
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Alzheimer Disease - Dementia |
| Purpose: |
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Alzheimer's disease often manifests as a memory disorder before dementia develops. Dementia
is considered to be present when a person can no longer handle complex activities of daily
living, such as managing finances. This study will investigate the relationship between
changes in the ability to manage finances and brain perfusion, which will be measured using
continuous arterial spin-labeling (an experimental MRI). Subjects will also undergo
neuropsychological tests focusing on several types of memory and thought process, with
special emphasis on semantic memory. An important question to be addressed is whether
changes in function are better predicted by the neuropsychological tests or by the brain
scan.
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| Study Summary: |
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| Criteria: |
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Inclusion Criteria:
- Veteran or non-veteran
- Age 50-89
- With normal cognition or memory impairment (MCI or mild AD)
- English speaking
- Right handed
- Adequate vision and hearing to take part in tests
- Able and willing to undergo MRI scan
- Medically and psychiatrically stable
- No other brain disease (such as tumor, Parkinson's disease, major stroke)
Exclusion Criteria:
- Pregnancy
- Inability to tolerate MRI (due to metal in body or claustrophobia)
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| NCT ID: |
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NCT00880555 |
| Primary Contact: |
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Principal Investigator
David G Clark, MD
VA Medical Center, Birmingham
David G Clark, MD
Phone: (205) 996-6050
Email: dgclark@uab.edu
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| Backup Contact: |
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Email: kathryn.burgio@va.gov
Kathryn L Burgio, PhD MA BA
Phone: (205) 933-8101 ext. 7307
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| Location Contact: |
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Birmingham, Alabama 35233
United States
David G Clark, MD
Phone: 205-996-6050
Email: dgclark@uab.edu
Site Status: Recruiting |
| Data Source: |
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ClinicalTrials.gov |
| Date Processed: |
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May 18, 2013 |
| Modifications to this listing: |
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