Sildenafil for Treatment of Priapism in Men With Sickle Cell Anemia

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City:		Baltimore
State:		Maryland
Zip Code:		21287

Conditions:		Sickle Cell Disease - Priapism
Purpose:		This research is being done to see if the drug sildenafil (Viagra) has an effect on the frequency of recurrent priapism and the quality of life in males with sickle cell disease.
Study Summary:
Criteria:		Inclusion Criteria: - Ages 14 to 45, inclusive - Episodes of prolonged penile erection in the absence of sexual interest or desire, with an average frequency of at least twice weekly, when averaged over the previous four weeks - Able to provide informed consent or assent Exclusion Criteria: - Use of chronic nitrates or recreational use of nitrate containing products - Use of a PDE5 inhibitor within the previous two weeks - Alcohol use exceeding two standard drinks daily - Hypersensitivity to sildenafil - Estimated glomerular filtration rate <50ml/min - Known cirrhosis - Retinitis pigmentosa - Necessary use of a P450 3A4 inhibitor
NCT ID:		NCT00940901
Primary Contact:		Principal Investigator Arthur L. Burnett, MD, MBA Johns Hopkins University Irene N. Trueheart, RN Phone: (443) 287-1011 Email: itruehe1@jhmi.edu
Backup Contact:		N/A
Location Contact:		Baltimore, Maryland 21287 United States Irene Trueheart, RN Phone: 443-287-1011 Email: itruehe1@jhmi.edu Site Status: Recruiting

Data Source:		ClinicalTrials.gov
Date Processed:		May 19, 2013
Modifications to this listing:		Only selected fields are shown, please use the link below to view all information about this clinical trial.
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