View Clinical Trial (Medical Research Study)
Prospective Assessment of Quality of Life (QOL) in Pediatric Patients Treated With Radiation Therapy for Brain Tumors and Non-CNS Malignancies
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Boston |
| State: |
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Massachusetts |
| Zip Code: |
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02114 |
| Conditions: |
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Brain Tumors - Non-CNS Malignancies |
| Purpose: |
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In recent years, remarkable advances in medical oncology, surgery, and radiology have
allowed for increasing cure rates for childhood malignancies. This success has led to an
emerging understanding of the kinds of effects that treatments can have on the pediatric
population and how such effects can influence pediatric cancer survivor's functioning and
quality of life. It has become tremendously important to assess the long-term complications
due to therapy in this growing sector of survivors and to tailor our treatments so as to
minimize these late effects.
The Investigators at MGH are committed to improving the delivery of radiotherapy to our
patients and improving the outcome for these patients. MGH has an on-site cyclotron for
proton radiotherapy in order to provide the most advanced care for patients in need. Proton
therapy possesses a clinical advantage over standard photon therapy in that its optimal dose
distribution delivers the bulk of radiation to the tumor site. This method spares the
greatest volume of normal tissue, resulting in decreased short-term and long-term morbidity.
Through open pediatric protocols for patients treated with proton radiotherapy, the
investigators aim to define and report the acute and late effects associated with treatment.
MD Anderson Cancer Center, another facility with an onsite proton facility, will be
collaborating with us on this portion of the study.
The investigators also treat a number of patients off-protocol with both proton and photon
radiotherapy, and are interested in reporting these patients' QOL outcomes in conjunction
with other clinical data that may be pertinent to the site of tumor treatment. This
research is significant in that it will allow us to delineate the positive and negative
effects of radiation treatment on patients' QOL, highlighting points of success and exposing
areas that are in need of improvement. Such knowledge will be used to improve the
experience of pediatric cancer survivors in the future.
The aims of this study are: 1) to prospectively collect and report the QOL outcomes in
patients treated with radiotherapy and 2) to correlate the QOL data with pertinent clinical
information.
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| Study Summary: |
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| Criteria: |
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Inclusion Criteria:
- Any patient being treated with radiation therapy with curative intent
- Patients between the ages of 2 and 25
- Patients who speak either English or Spanish
- Patients who agree to fill out the questionnaire
Exclusion Criteria:
- Patients younger than 2 years of age or over 25
- Patients receiving treatment with palliative intent
- Patients who do not wish to participate
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| NCT ID: |
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NCT01115777 |
| Primary Contact: |
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Principal Investigator
Torunn Yock, MD
Massachusetts General Hospital
Torunn I Yock, MD
Phone: 617-726-5184
Email: TYOCK@PARTNERS.ORG
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| Backup Contact: |
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N/A |
| Location Contact: |
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Boston, Massachusetts 02114
United States
There is no listed contact information for this specific location.
Site Status: Recruiting |
| Data Source: |
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ClinicalTrials.gov |
| Date Processed: |
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May 21, 2013 |
| Modifications to this listing: |
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