Spectroscopic and Colorimetric Analysis of Acanthosis Nigricans in Patients With Hyperinsulinemia
This study is not currently recruiting Study Participants on ClinicalConnection.com. If you would like to find active studies please search for clinical trials
| City: |
|
Detroit |
| State: |
|
Michigan |
| Zip Code: |
|
48202 |
| Conditions: |
|
Acanthosis Nigricans - Hyperinsulinemia - Spectroscopic Analysis |
| Purpose: |
|
Acanthosis Nigricans is skin disease that associated with hyperinsulinemia. Clinical is
velvety hyperpigmented plaques on neck, axilla, groin. If hyperinsulinemia is improved by
treated with oral metformin and/ or diet control, acanthosis nigricans would be improved as
well. Hyperpigmented plaques will be changed. We assess objective measurement by using
spectroscopic and colorimetric analysis.
|
| Study Summary: |
|
|
| Criteria: |
|
Inclusion Criteria:
1. Subjects must have an elevated fasting insulin level, suggesting they are in an
insulin resistant state.
2. Subjects must carry a diagnosis of acanthosis nigricans, which will be verified by a
Dermatologist before entry into the study. If necessary, a small 4mm punch biopsy may
be taken to document dermatopathology consistent with acanthosis nigricans.
3. Subjects must be willing and able to undergo treatment with Metformin, including
initial referral and follow up.
4. Agree to abide by the investigator's guidelines
5. Be able to understand the requirements of the study, the risks involved and are able
to sign the informed consent form
6. Agree to follow and undergo all study-related procedures
Exclusion Criteria:
1. Subjects with Type 1 Diabetes are excluded because of their naturally
insulin-deficient, rather than hyper-insulinemic, states.
2. Women who are lactating, pregnant, or planning to become pregnant.
3. Any reason the investigator feels the patient should not participate in the study.
-
|
| NCT ID: |
|
NCT01125150 |
| Primary Contact: |
|
Principal Investigator
Iltefat Hamzavi, M.D.
Department of Dermatology, Henry Ford Hospital
|
| Backup Contact: |
|
N/A |
| Location Contact: |
|
Detroit, Michigan 48202
United States
There is no listed contact information for this specific location.
Site Status: N/A |
| Data Source: |
|
ClinicalTrials.gov |
| Date Processed: |
|
May 22, 2013 |
| Modifications to this listing: |
|
Only selected fields are shown, please use the link
below to view all information about this clinical trial. |
|
Click to view Full Listing
|