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Absorption of "ABH Gel" (Ativan®, Lorazepam; Benadryl®, Diphenhydramine; and Haldol®, Haloperidol Gel) From the Skin of Normal Volunteers

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City:   Richmond
State:   Virginia
Zip Code:   23298
Conditions:   Nausea and Vomiting
Purpose:   RATIONALE: Lorazepam, diphenhydramine hydrochloride, and haloperidol gel, when absorbed into the skin, may be an effective treatment for nausea and vomiting.PURPOSE: This clinical trial studies lorazepam, diphenhydramine hydrochloride, and haloperidol gel in healthy volunteers.
Study Summary:   OBJECTIVES:I. To study the absorption of the three components in the topical ABH gel in 10 healthy volunteers, and determine if there are any adverse effects. OUTLINE: Patients apply lorazepam, diphenhydramine hydrochloride, and haloperidol gel topically over 2 minutes. After completion of study treatment, patients are followed up for 5 hours.
Criteria:   Inclusion Criteria: - Completed a medical screening questionnaire - English speaking - No allergies to the drugs - Able to complete the forms - If a woman of childbearing age, agree to use contraception Exclusion Criteria: - History of substance abuse, psychiatric disorder, acquired brain injury, the possibility of pregnancy (not using birth control, and of child bearing age) - Use of any medication that would contraindicate benzodiazepine administration - Pregnant or nursing
NCT ID:   NCT01204255
Primary Contact:   Principal Investigator
Thomas Smith
Virginia Commonwealth University

Backup Contact:   N/A
Location Contact:   Richmond, Virginia 23298
United States



There is no listed contact information for this specific location.

Site Status: N/A

Data Source:   ClinicalTrials.gov
Date Processed:   March 31, 2015
Modifications to this listing:   Only selected fields are shown, please use the link below to view all information about this clinical trial.
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