View Clinical Trial (Medical Research Study)
Pilot Program to Improve Statin Adherence and Lower Cholesterol in Older Adults
| City: |
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Columbia |
| State: |
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Missouri |
| Zip Code: |
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65211 |
| Conditions: |
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Hypercholesterolemia - Medication Adherence |
| Purpose: |
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The purpose of this study is to pilot test a behavioral medication adherence (MA)
intervention compared to control condition in older adults with low adherence to medication
for hypercholesterolemia.
This study will answer the following primary research question:
1. What is the estimated effect size of a behavioral MA intervention on MA rates in older
adults who are poorly adherent to statin medications?
The study will also explore the following secondary research questions:
2. What is the estimated effect size of a behavioral MA intervention on low-density
lipoprotein cholesterol (LDL-C) levels in older adults?
3. What is the estimated effect size of a behavioral MA intervention on high-density
lipoprotein cholesterol (HDL-C) levels in older adults?
4. What is the feasibility of successfully testing this intervention protocol in a
population of older adults with low adherence to statin medications?
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| Study Summary: |
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| Criteria: |
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Inclusion Criteria:
- Age 60 or older at the time of study entry,
- Take a once-daily prescription statin medication for ≥ 6 months with no changes to
statin prescription for at least 30 days prior to study entry,
- A score of ≤ 9 on the Short Blessed Test,
- Participants must self-administer his or her own medications without prompts from any
other person or device.
- Baseline medication adherence rate of ≤ 90%.
- Participants agree to complete all study contacts and measurements, including the use
of a special medication bottle with a Medication Event Monitoring System (MEMS) cap
for the duration of the study.
- Able to open and close MEMS caps.
Exclusion Criteria:
- Participant's medications are managed by someone other than the participant
- Participant is unable or unwilling to use MEMS caps.
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| NCT ID: |
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NCT01227330 |
| Primary Contact: |
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Principal Investigator
Todd Ruppar, PhD, RN
University of Missouri-Columbia
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| Backup Contact: |
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N/A |
| Location Contact: |
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Columbia, Missouri 65211
United States
Todd Ruppar, PhD, RN
Phone: 573-884-5153
Email: ruppart@missouri.edu
Site Status: Recruiting |
| Data Source: |
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ClinicalTrials.gov |
| Date Processed: |
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May 21, 2013 |
| Modifications to this listing: |
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