View Clinical Trial (Medical Research Study)

Efficacy and Safety of Brinzolamide 1% / Brimonidine 0.2% Fixed Combination BID vs. Brinzolamide 1% BID Plus Brimonidine 0.2% BID

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Conditions:		Open-angle Glaucoma or Ocular Hypertension
Purpose:		A multi-center, double-masked, randomized parallel group efficacy and safety study of brinzolamide 1% /brimonidine 0.2% fixed combination compared to brinzolamide 1% plus brimonidine 0.2% in patients with open-angle glaucoma or ocular hypertension.
Study Summary:
Criteria:		Inclusion Criteria: - Patients 18 years of age or older, of either gender, and any race/ethnicity, diagnosed with open-angle glaucoma or ocular hypertension who in the opinion of the Investigator are insufficiently controlled on monotherapy or are currently on multiple IOP-lowering medications. - Patients meeting qualifying IOP entry criteria. - Able to understand and sign an informed consent form that has been approved by an Institutional Review Board/Independent Ethics Committee. Exclusion Criteria: - Schaffer angle Grade < 2 - Cup/disc ratio greater than 0.80 - Severe central visual field loss - Best Corrected VA score worse than 55 ETDRS letters (20/80 Snellen equivalent) - Chronic, recurrent or severe inflammatory eye disease - Clinically significant or progressive retinal disease - Other ocular pathology - Patients with recent use of high-dose (>1 gm daily) salicylate therapy - Recent, current, or anticipated treatment with any medication that augments adrenergic responses, or precludes use of an alpha-adrenergic agonist
NCT ID:		NCT01309204
Primary Contact:		N/A
Backup Contact:		N/A
Location Contact:		Fort Worth, Texas 76134 United States There is no listed contact information for this specific location. Site Status: N/A

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