Permissive Hypercapnia and Brain Development in Premature Infants

Conditions:		Premature Birth
Purpose:		In the US, every year approximately 30,000 infants are born very prematurely, with birth weight less than 1000 grams. These infants usually require ventilators to help them breath normally during the first few weeks of life. Although the ventilator is lifesaving, it can also injure the very fragile lungs of these infants. Thus, a ventilation strategy, called permissive hypercapnia (high carbon dioxide), is widely used to prevent lung injury. Importantly, there is new research showing that high carbon dioxide may cause brain injury. In our proposed research, we will use magnetic resonance imaging methods to evaluate the brain in 40 very premature infants at term−equivalent age (Half of them had permissive hypercapnia ventilation, the other half did not) to see if permissive hypercapnia has adverse effect on brain development.
Study Summary:
Criteria:		Inclusion Criteria: - Premature infants with birth weight 401-1000 g Exclusion Criteria: - Those with complex congenital anomalies, central nervous system malformations, chromosomal abnormalities, or hydrops fetalis
NCT ID:		NCT01361360
Primary Contact:		N/A
Backup Contact:		N/A
Location Contact:		Little Rock, Arkansas 72211 United States Xiawei Ou, PhD Email: ouxiawei@uams.edu Site Status: Recruiting

Data Source:		ClinicalTrials.gov
Date Processed:		June 18, 2013
Modifications to this listing:		Only selected fields are shown, please use the link below to view all information about this clinical trial.
Click to view Full Listing


If you would like to be contacted by the clinical trial representative please enter your contact information, then click "I Am Interested In This Study"

First Name:

Last Name:

Email Address:

Confirm Email:

Daytime Phone (eg. 555-555-5555):

City:

State:

Zip Code:

Best Time to Call:

Morning	Afternoon	Evening
Please contact me by email instead of calling.

Questions/Comments:

I have read and agree with the Privacy Policy

I have reviewed the eligibility criteria and believe I am eligible for this clinical trial

I would like to be notified about new clinical trials.

ClinicalConnection.com is a resource that provides individuals with information regarding clinical trials that are being conducted worldwide.

ClinicalConnection.com does not conduct these clinical trials nor endorse them. Please consult your doctor or physician before participating.