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Inclusion Criteria:
1. Inclusion Criteria for the entire trial:
- Women and men aged 18-65, inclusive, who are competent, wish to participate and
willing to provide informed consent.
- Self report smoking >=15 cigarettes/day.
- Expired air CO > 9ppm at the time of enrollment.
- Must be willing to participate in a meditation training group.
2. Inclusion criteria for the physiological assessment:
- Abstinent for at least 12 hrs prior to the assessment.
- CO<15ppm
- Have negative urine toxicology for illicit drugs or alcohol.
Exclusion Criteria:
- DSM-IV diagnosis of dementia, neurodegenerative disease, or other organic mental
disorder, lifetime history of psychotic disorder, bipolar disorder, severe PTSD,
Dissociative Identity Disorder, OCD, anorexia nervosa, mental retardation, or autism.
- History of moderate or severe major depressive episode or generalized anxiety
disorder within the last 6 months.
- Use of prescribed psychotropic medication other than SSRI/NDRI/SNRI/ buprenorphine in
past 6mo, or change in such psychiatric medication dose in past six months.
- History of active substance use disorder other than nicotine or caffeine in the last
6 months.
- Positive urine toxicology for illicit drugs, alcohol, opiates or benzodiazepines.
- Serious unstable medical illness including, cardiovascular, hepatic, renal,
respiratory, endocrine, neurological, or hematological disease such that
hospitalization for treatment of that illness is likely within the next 4 months.
History of life-threatening arrhythmia, CHF, syncope, or myocardial infarction within
the last year. Abnormal cardiovascular event, or uncontrolled hypertension within
last 2 months.
- History of cerebro-vascular events (i.e., stroke, TIA), multiple head injuries with
neurological sequelae, a single severe head injury with lasting neurological
sequelae, history of seizure disorder or current CNS tumor.
- Use of investigational medication in the past 30 days.
- Inability to speak, read, or understand English.
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