View Clinical Trial (Medical Research Study)
Responsiveness to Dalfampridine Treatment Among Multiple Sclerosis Patients Followed at the Mandell MS Center: Characterizing Clinical Predictors of Response and Identifying Additional Outcomes
| City: |
|
Hartford |
| State: |
|
Connecticut |
| Zip Code: |
|
06112 |
| Conditions: |
|
Multiple Sclerosis |
| Purpose: |
|
Ampyra (dalfampridine) has been recently approved by the FDA for improving walking speed in
persons with multiple sclerosis. However, only 35%-45% of persons with multiple sclerosis
who take the drug show and increase in walking speed. This project seeks (1) to determine
factors that will predict a response (an increase in walking speed) to dalfampridine and (2)
to determine if there are other benefits to taking dalfampridine besides an increase in
walking speed. This is strictly an observational study and research staff will not be
involved in any decisions to stop are start taking the medication.
|
| Study Summary: |
|
|
| Criteria: |
|
Inclusion Criteria:
- Confirmed clinical diagnosis of MS by McDonald criteria
- Prescribed ampyra (dalfampridine) as part of usual care, but have not yet started
taking the medication before baseline visit
- Receive MS care at the Mandell MS center
- Cognitively able to understand directions and complete protocol (score of 22 or
greater on the MMSE)
- 18 years of age or older
Exclusion Criteria:
- Already began to take drug prior to baseline research visit
- Not planning to continue care at Mandell Center for at least 14 weeks after
initiation of therapy
- Unwilling or unable to complete assessments
|
| NCT ID: |
|
NCT01399957 |
| Primary Contact: |
|
Principal Investigator
Albert Lo, M.D, Ph.D.
Mandell Center for Multiple Sclerosis at Mount Sinai Rehabilitation Hospital
Jennifer Ruiz, BS
Phone: 860-714-2149
|
| Backup Contact: |
|
Michele Labas, BA
Phone: 860-714-2149
|
| Location Contact: |
|
Hartford, Connecticut 06112
United States
Jennifer Ruiz
Phone: 860-714-2149
Site Status: Recruiting |
| Data Source: |
|
ClinicalTrials.gov |
| Date Processed: |
|
May 17, 2013 |
| Modifications to this listing: |
|
Only selected fields are shown, please use the link
below to view all information about this clinical trial. |
|
Click to view Full Listing
|