View Clinical Trial (Medical Research Study)
Randomized Controlled Trial of 2% Chlorhexidine Bathing on Nosocomial Infections in the Surgical Intensive Care Unit
| City: |
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Houston |
| State: |
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Texas |
| Zip Code: |
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77030 |
| Conditions: |
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Cross Infection - Pneumonia, Ventilator-associated - Catheter-related Infections - Infection Due to Indwelling Urinary Catheter - Surgical Wound Infection |
| Purpose: |
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This prospective, randomized, controlled trial will compare the incidence of nosocomial
infections (composite of primary bloodstream infections, catheter-associated urinary tract
infections, ventilator-associated pneumonia, and surgical site infections) that occur in
intensive care unit (ICU) patients bathed with 2% chlorhexidine solution versus patients who
receive standard bathing (soap and water or non-medicated cloths).
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| Study Summary: |
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Upon study enrollment, patients will be randomized to one of two study arms. Patients in
study arm one will receive standard bathing (soap and water or non-medicated cloth) daily.
Patients in study arm two will receive a 2% chlorhexidine bath on study day 1 and every 48
hours and a standard bath (soap and water or non-medicated cloths) on study day 2 and every
48 hours. Patients will be followed until ICU day 28 or discharged from the surgical ICU.
Hypothesis: Compared to standard daily bathing, chlorhexidine-based bathing on ICU admission
and every 48 hours will decrease the incidence of nosocomial infections.
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| Criteria: |
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Inclusion Criteria:
- Admission to the surgical intensive care unit at The Methodist Hospital (Houston, TX)
- Anticipated surgical intensive care unit length of stay of 48 hours or more
Exclusion Criteria:
- Pregnancy
- Age less than 18 years old
- Braden score of less than 9 upon admission to the surgical intensive care unit
- Known allergy to chlorhexidine gluconate
- Active skin irritation upon admission to the surgical intensive care unit
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| NCT ID: |
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NCT01640925 |
| Primary Contact: |
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Principal Investigator
Joshua T Swan, Pharm.D.
The Methodist Hospital, Texas Southern University
Joshua T Swan, Pharm.D.
Phone: 713-313-1217
Email: jtswan@tmhs.org
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| Backup Contact: |
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Email: skung@tmhs.org
Shirley Kung, R.N.
Phone: 713-441-6348
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| Location Contact: |
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Houston, Texas 77030
United States
Joshua T Swan, Pharm.D.
Phone: 713-313-1217
Email: jtswan@tmhs.org
Site Status: Recruiting |
| Data Source: |
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ClinicalTrials.gov |
| Date Processed: |
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May 21, 2013 |
| Modifications to this listing: |
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