Brain Study of Patients With Frontal Lobe Dementia and Parkinsonian Disorders - NCT00001178-20892 (Clinical Trial 111114)
Permalink: http://www.ClinicalConnection.com/exp/ExpandedPatientViewStudy111114.aspx
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| City: |
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Bethesda |
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State:
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MD |
| Zip Code: |
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20892 |
| Conditions: |
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Alzheimer's Disease - Dementia - Down's Syndrome |
| Purpose: |
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The Cognitive Neuroscience Section of the National Institute of Neurological Disorders and
Stroke proposes to continue its cross-sectional and longitudinal studies of cerebral
metabolism in frontal lobe dementias and atypical basal ganglia disorders. These studies
include repeated assessments of neuropsychological and brain anatomical and metabolic
function in subjects with these important and possibly related brain disorders.
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| Study summary: |
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Objective
To continue the cross-sectional and longitudinal studies performed by the Cognitive
Neuroscience Section of NINDS on the neuroanatomy, cerebral metabolism, neuropsychology, and
genetics of frontotemporal dementia, corticobasal syndrome, and related brain disorders.
Study population
Frontal lobe dementias and atypical basal ganglia disorders including frontotemporal
dementia, corticobasal syndrome, and related brain disorders.
Design
A cross-sectional assessment of neuropsychological, brain anatomical and metabolic function,
and genetic measures in subjects with these disorders.
Outcome measures
MRI, FDG-PET, neuropsychological and clinical tests, genetics, and neuropathology. |
| Criteria: |
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- Subjects will be recruited from the NIH referral center, neurological and psychiatric
clinics, from self or family referral in response to advertisements or from private
physicians. Healthy volunteers will include subjects who are considered aT-risk for
the development of FTD or CBS and subjects who serve as normal controls matched for
key characteristics with the patients.
INCLUSION CRITERIA FOR PATIENTS:
- Diagnosis of possible / probable FTD or CBS
- Caregiver willing and able to accept the responsibilities involved in the study
EXCLUSION CRITERIA:
- Pregnant women. Women of childbearing potential will be screened by history for the
possibility of pregnancy and undergo a urine pregnancy test. These women will be
excluded from the imaging portions of the protocol.
- Behavioral symptoms that would preclude the gathering of data for the study
- Other medical or social condition that would preclude participation in the opinion of
the investigators |
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| Study is available at: |
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National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, MD 20892
United States
Primary Contact:
Patient Recruitment and Public Liaison Office
Email: prpl@mail.cc.nih.gov
Phone: (800) 411-1222 |
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If you are interested in this clinical trial please use the contact information above. If you would like to get additional information about this clinical trial please visit ClinicalTrials.gov.
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| Data Source: |
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ClinicalTrials.gov |
| Date Processed: |
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March 15, 2010 |
Modifications to
this listing: |
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Only selected fields are shown, please use the link
above to view all information about this clinical trial. |
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Clinical trials are medical research studies designed to test the safety and/or
effectiveness of new drugs, devices, or treatments in humans. These studies are
conducted worldwide for a range of conditions and illnesses. Learn more about
clinical research and participating in a study at
About Clinical Trials.
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