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Estrogen and Perimenopausal Depression - NCT00229450-90024(Clinical Trial 131385)



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City:  Los Angeles
State:  
CA
Zip Code: 90024
Conditions: Depressive Disorder, Major - Menopause
Purpose: During perimenopause (the time just prior to menopause), women often notice many biological, psychological, and social changes. In particular, some women experience depressive symptoms during perimenopause that are severe enough to warrant antidepressant medication. Whether or not women with perimenopausal depression respond to antidepressant medication may depend on the level of estrogen in their blood. We would like to investigate whether estrogen will help the women who only partially respond to antidepressant medications. We also want to examine how different doses of estrogen may affect individuals differently.
Study summary:
Criteria: Inclusion Criteria: - Clinical Diagnosis of Unipolar Major Depression, currently taking antidepressants - HAM-D between 10 and 17 Exclusion Criteria: - History of Psychosis, breast cancer, smoking, dementia, clotting disorders - Current substance abuse
Study is available at: UCLA Neuropsychiatric Institute & Hospital
Los Angeles, CA 90024
United States

Primary Contact:
Jodie B. Cohen, B.S.
Email: jodie@mentalhealth.ucla.edu
Phone: 310-825-0528

Secondary Contact:
Melinda L. Morgan, Ph.D.
Email: melinda@ucla.edu
Phone: 310-825-5028
If you are interested in this clinical trial please use the contact information above. If you would like to get additional information about this clinical trial please visit ClinicalTrials.gov.
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Data Source: ClinicalTrials.gov
Date Processed: March 21, 2011
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