View Clinical Trial (Medical Research Study)
Estrogen and Perimenopausal Depression - NCT00229450-90024(Clinical Trial 131385)
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Los Angeles |
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State:
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CA |
| Zip Code: |
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90024 |
| Conditions: |
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Depressive Disorder, Major - Menopause |
| Purpose: |
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During perimenopause (the time just prior to menopause), women often notice many biological,
psychological, and social changes. In particular, some women experience depressive symptoms
during perimenopause that are severe enough to warrant antidepressant medication. Whether
or not women with perimenopausal depression respond to antidepressant medication may depend
on the level of estrogen in their blood. We would like to investigate whether estrogen will
help the women who only partially respond to antidepressant medications. We also want to
examine how different doses of estrogen may affect individuals differently.
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| Study summary: |
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| Criteria: |
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Inclusion Criteria:
- Clinical Diagnosis of Unipolar Major Depression, currently taking antidepressants
- HAM-D between 10 and 17
Exclusion Criteria:
- History of Psychosis, breast cancer, smoking, dementia, clotting disorders
- Current substance abuse |
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| Study is available at: |
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UCLA Neuropsychiatric Institute & Hospital Los Angeles, CA 90024 United States
Primary Contact: Jodie B. Cohen, B.S. Email: jodie@mentalhealth.ucla.edu Phone: 310-825-0528
Secondary Contact: Melinda L. Morgan, Ph.D. Email: melinda@ucla.edu Phone: 310-825-5028 |
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If you are interested in this clinical trial please use the contact information above. If you would like to get additional information about this clinical trial please visit ClinicalTrials.gov.
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| Data Source: |
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ClinicalTrials.gov |
| Date Processed: |
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March 21, 2011 |
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