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Data and Sample Collection Study to Elucidate the Mechanisms of Eosinophilic Disorders - NCT00267501-45229(Clinical Trial 134956)



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City:  Cincinnati
State:  
OH
Zip Code: 45229
Conditions: Eosinophilic Gastrointestinal Disease Eosinophilic Inflammatory Disease - Food Allergy
Purpose: The purpose of this study is to elucidate the mechanisms underlying eosinophil growth, survival, migration, and function and to investigate and further characterize the pathophysiology of, clinical manifestations of, and spectrum of disease severity of eosinophilic inflammation in humans.
Study summary:
Criteria: Inclusion Criteria: - Signed informed consent obtained from the patient or parent/guardian. Assent will be obtained from all minors 11 years of age and older. - Age 1-65 years. - Carrying a diagnosis of eosinophilic gastrointestinal disease, eosinophilic inflammatory disease, or food allergy - Other inclusion criteria may include: undergoing endoscopy based on evaluation by a pediatric CCHMC gastroenterologist Exclusion Criteria: - Recent viral infection (in preceding 1-2 weeks) such as upper respiratory tract infection, tonsillitis, or gastroenteritis. Viral infections in general may suppress or alter some cellular responses, especially lymphocyte responses in vivo. - Oral or esophageal infections including candidiasis in the preceding 2 weeks - Known diagnosis of another systemic or gastrointestinal inflammatory condition including, but not limited to, ulcerative colitis, Crohn's disease, indeterminate colitis, celiac disease, cystic fibrosis, or immunodeficiency. - Concurrent use of systemic steroids, antihistamines, or other immunomodulatory drugs that may alter cellular responses. - Concurrent use of anticoagulant medications which may alter cellular responses.
Study is available at: Cincinnati Children's Hospital Medical Center
Cincinnati, OH 45229
United States

Primary Contact:
Tommie M Grotjan, M.S.
Email: tommie.grotjan@cchmc.org
Phone: 513-803-1655
If you are interested in this clinical trial please use the contact information above. If you would like to get additional information about this clinical trial please visit ClinicalTrials.gov.
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Data Source: ClinicalTrials.gov
Date Processed: March 21, 2011
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