Familial Barrett's Esophagus - NCT00288119-44195 (Clinical Trial 137425)
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| City: |
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Cleveland |
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State:
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OH |
| Zip Code: |
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44195 |
| Conditions: |
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Barrett's Esophagus - Esophageal Neoplasm |
| Purpose: |
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This is a multi-center study whose aim is to define the epidemiology and genetics of
Barrett's esophagus and adenocarcinoma. The researchers have studied families affected with
Barrett's esophagus and esophageal adenocarcinoma, a specific type of cancer of the
esophagus. They have found that Barrett's and esophageal cancer occur at a younger age in
these families suggesting that familial Barrett's esophagus is a genetically inherited
disease.
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| Study summary: |
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This research study is trying to determine whether Barrett's esophagus and associated
esophageal cancers, specifically esophageal adenocarcinoma are inherited in certain
families. Persons who are affected with Barrett's esophagus or esophageal cancer
(adenocarcinoma type) are asked to complete a questionnaire that determines their habits and
asks a detailed family history. Family members of patients seen at University Hospitals of
Cleveland and the Cleveland Clinic are also being recruited for screening tests of their
esophagus. The investigators plan to eventually screen family members at all participating
institutions. This research will eventually lead to the identification of inherited genetic
changes that cause Barrett's esophagus and esophageal cancer. It will help the
investigators develop better methods for preventing or identifying esophageal cancer at an
early curable stage. |
| Criteria: |
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Eligible cases will be defined as those patients and their family members who meet the
following criteria:
- Barrett's esophagus confirmed by review of pathology and endoscopy report or
adenocarcinoma of the esophagus or family members of person with Barrett's esophagus
or adenocarcinoma of the esophagus.
- Male or female age 18 or older at time of enrollment or male or female less than 18
years of age at time of enrollment with parental consent.
- Ability to give informed consent, if patient is age 18 or older. |
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If you are interested in this clinical trial please use the contact information above. If you would like to get additional information about this clinical trial please visit ClinicalTrials.gov.
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| Data Source: |
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ClinicalTrials.gov |
| Date Processed: |
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January 18, 2010 |
Modifications to
this listing: |
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Only selected fields are shown, please use the link
above to view all information about this clinical trial. |
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Clinical trials are medical research studies designed to test the safety and/or
effectiveness of new drugs, devices, or treatments in humans. These studies are
conducted worldwide for a range of conditions and illnesses. Learn more about
clinical research and participating in a study at
About Clinical Trials.
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