View Clinical Trial (Medical Research Study)
Efficacy of Proprietary Cherry Juice Blend in Osteoarthritis of the Knee - NCT00443092-19104(Clinical Trial 164501)
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Philadelphia |
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State:
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PA |
| Zip Code: |
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19104 |
| Conditions: |
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Osteoarthritis |
| Purpose: |
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The primary purpose of this research study is to test the ability of a proprietary cherry
juice blend to be helpful in the treatment of osteoarthritis (OA) of the knee.
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| Study summary: |
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The primary objective is to determine if the proprietary tart cherry juice blend improves
the pain and function in persons with knee osteoarthritis. A secondary objective is to
ascertain if the blend lowers serum uric acid.
This is a prospective double blind, placebo controlled cross-over study.
The study will be performed in the Philadelphia VA Medical Center 1 South Rheumatology
Clinic with patients meeting ACR criteria for Kellgren grade 2-3 knee osteoarthritis and 4-9
pain severity on a VAS. Fifty patients will be studied with each having 5 visits. Subjects
will take either the proprietary cherry blend or placebo for 6 weeks and then switch. WOMAC
pain and function will be the primary outcome with acetaminophen use, walking time and serum
uric acid as secondary outcomes. |
| Criteria: |
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Inclusion Criteria:
- Subject is capable of giving informed consent.
- Subject is over 18 years and less than 80 years
- Subject has mild to moderate osteoarthritis of the knee based on all of the following
3:
1. Meets clinical ACR criteria
2. Kellgren score of 2-3 on a Standing Knee x-ray within previous 24 months
3. VAS pain score of 4-9 at screening visit
Exclusion Criteria:
- Rheumatoid arthritis or other systemic inflammatory condition
- Chronic pain syndrome (fibromyalgia)
- Corticosteroid medication in last 2 months, either intra-articular or oral
- Intra-articular injections of hyaluronic acid in last 9 months
- Pregnant women (weight gain might confound degree of knee pain)
- Diabetes
- Inability to discontinue prescription medication for arthritis
- Unstable medical conditions that would likely prevent the subject from completing the
study
- Food allergies - cherries, apples |
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If you are interested in this clinical trial please use the contact information above. If you would like to get additional information about this clinical trial please visit ClinicalTrials.gov.
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| Data Source: |
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ClinicalTrials.gov |
| Date Processed: |
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August 3, 2010 |
Modifications to
this listing: |
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Only selected fields are shown, please use the link
above to view all information about this clinical trial. |
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