View Clinical Trial (Medical Research Study)

Research Study for Children With a Mother or Sister With Polycystic Ovary Syndrome - NCT00559390-60611(Clinical Trial 191290)



ClinicalConnection.com has recently undergone an update and this page may no longer be up-to-date. Please Search For Clinical Trials to view the most current clinical trials listings.


Signup
City:  Chicago
State:  
IL
Zip Code: 60611
Conditions: Precursors to PCOS
Purpose: In this study, we want to find out more about polycystic ovary syndrome(PCOS). This is a common problem in about 7% of teenage girls. Problems may include irregular periods, extra hair on the face, chest and back areas. It seems that PCOS is related to a high level of male hormones and to another problem called metabolic syndrome(MBS). People with MBS may have high blood pressure, low good cholesterol, high blood fats and extra fat around the waist. Girls with MBS are at high risk for getting diabetes and heart disease.
Study summary: Once enrolled in the study, you will have a physical exam done. This includes getting a medical history, height, weight, blood pressure and heart rate. We will also listen to your heart and lungs. We will also look at your skin and determine what stage of puberty you are in by looking at your breast growth and body hair. You will also have two (maybe three) blood tests. The first one is an oral glucose tolerance test (OGTT). During this test, we will have you drink an orange sugary drink and then we will draw your blood. The second test is a frequently sampled intravenous glucose tolerance test (FSIGT). During this test, we will give you insulin through one IV catheter and then we will draw blood from another IV catheter. The third test that you might have done is an ACTH test. During this test, we will draw your blood and then you will be given a dose of cortrosyn (a hormone that your body already makes) and then we will draw your blood again. You will also have two scans of your body done during your visit. There will be a Dual Energy X-Ray Scan (DEXA) and a Magnetic Resonance Imaging Scan (MRI). You will be placed in the machines and then the scanner will move over your body.
Criteria: Inclusion Criteria: - Relatives with polycystic ovary syndrome - No relatives with polycystic ovary syndrome - Overweight - White non-hispanic girls Exclusion Criteria: - Chronic Illness - Smokers - Already having periods
Study is available at: Northwestern University
Chicago, IL 60611
United States

Primary Contact:
Andrea Dunaif, MD
Email: a-dunaif@northwestern.edu
Phone: 312-503-2902

Secondary Contact:
Andrea Dunaif, MD
Email: a-dunaif@northwestern.edu
Phone: 312-503-2902
If you are interested in this clinical trial please use the contact information above. If you would like to get additional information about this clinical trial please visit ClinicalTrials.gov.
Trials Alerts: If you would like to be notified of new clinical trials as they become available please register for a free account.
Data Source: ClinicalTrials.gov
Date Processed: March 22, 2011
Modifications to
this listing:		 Only selected fields are shown, please use the link above to view all information about this clinical trial.