|
|
View Clinical Trial (Medical Research Study)
|
Effectiveness of Behavioral Treatments for Obesity and Major Depression in Women - NCT00572520-01655 (Clinical Trial 194898)
Permalink: http://www.ClinicalConnection.com/exp/ExpandedPatientViewStudy194898.aspx
|
** Please review additional "Nearby Studies" on right ----->
This is an archived study that is no longer available, if you
would like to find active studies please
search our studies.
|
|
 |
 |
|
| City: |
|
Worcester |
|
State:
|
|
MA |
| Zip Code: |
|
01655 |
| Conditions: |
|
Depression - Obesity |
| Purpose: |
|
This study will compare the effectiveness of two weight loss programs, one supplemented with
health education and the other supplemented with behavioral counseling, in treating women
who are depressed and overweight.
|
| Study summary: |
|
Obesity is one of the most alarming current health problems in the United States, with 31%
percent of the population considered obese. Previous studies have shown that there is a
higher incidence of depression in people who are overweight. It is not known whether
depression causes obesity or vice versa, but the association may stem from the stigma of
obesity or from the appetite and weight gain caused by depressive symptoms. With the
increased risk of cardiovascular and other life-threatening diseases from obesity, promotion
of healthful habits is important. Providing the motivational skills to adhere to these
habits is also crucial, especially in people who are both overweight and depressed. This
study will compare the effectiveness of two weight loss programs, one supplemented with
health education and the other supplemented with behavioral counseling, in treating women
who are depressed and overweight.
Participants in this 2-year study will be divided into one of two treatment groups: one
group will address weight loss and depression via nutrition, exercise, and health education
and the other group will address weight loss and depression via nutrition, exercise, and
behavioral counseling. Participants receiving health education will learn about women's
health topics and receive tips on staying healthy and preventing disease. Participants
receiving behavioral counseling will learn about depression and links between activity and
mood. They will also be asked to keep a diary of moods and activities. Participants in both
treatment groups will undergo the same schedule of study visits and assessments. A baseline
visit will include blood tests; measurements of height, weight, waist size, and blood
pressure; and completion of questionnaires about depression, eating habits, and physical
activity. Next, over a 3-week period, participants will receive three phone calls asking
about food intake from the previous day. In the first 6 months of the study, there will be a
total of 26 weekly treatment visits. These visits will consist of ten 1-hour sessions with a
counselor and sixteen 90-minute sessions with a dietician. During the next 6 months,
participants will continue to meet with their dieticians monthly for a total of 6 visits and
will receive monthly phone calls from their counselor. Monthly visits with the dietician
will continue in the second year of the study and phone calls will continue quarterly. There
will be three check-in appointments similar to the baseline assessment, occurring at Month 6
and Years 1 and 2. |
| Criteria: |
|
Inclusion Criteria:
- Meets DSM-IV criteria for major depressive disorder
- Score of 12 to 24 on Hamilton Depression Rating Scale (HDRS)
- Body mass index (BMI) of 30 to 40 kg
Exclusion Criteria:
- Plans to move out of the area during the study
- Current smoker
- Diagnosis of bipolar disorder, a psychotic disorder, bulimia, or post-traumatic
stress disorder
- Meets criteria for severe depression (HDRS score greater than 24)
- Diagnosis of type 1 or 2 diabetes
- Plans to have bariatric surgery during the study
- No access to a telephone
- Unable to walk unaided or unable to walk 1/4 mile without stopping
- Does not have written clearance from primary care physician for physical activity
- Presence of a condition that precludes dietary changes (e.g., ulcerative colitis,
Crohn's disease, active diverticulitis, renal disease)
- Presence of medical conditions likely to limit lifespan
- Taking prescription weight loss medications
- Initiation of anti-depressant medication within the 3 months prior to study entry
- Taking mood stabilizers, antipsychotic medication, or medications known to affect
appetite and/or weight (e.g., corticosteroids)
- Reports active suicidal ideation via SCID interview, a score of 3 on item 24 of the
HDRS (active suicidal ideation), or determined to have suicidal potential by clinical
staff
- Psychiatric hospitalization in the 12 months prior to study entry
- Currently receiving psychotherapy |
|
|
|
|
|
|
|
|
If you are interested in this clinical trial please use the contact information above. If you would like to get additional information about this clinical trial please visit ClinicalTrials.gov.
|
| Trials Alerts: |
|
If you would like to be
notified of new clinical trials as they become available please
register for a free account.
|
|
| Data Source: |
|
ClinicalTrials.gov |
| Date Processed: |
|
November 4, 2009 |
Modifications to
this listing: |
|
Only selected fields are shown, please use the link
above to view all information about this clinical trial. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| |
|
|
| |
|
|
| |
|
|
| |
|
|
| |
|
|
| |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Clinical trials are medical research studies designed to test the safety and/or
effectiveness of new drugs, devices, or treatments in humans. These studies are
conducted worldwide for a range of conditions and illnesses. Learn more about
clinical research and participating in a study at
About Clinical Trials.
|
|
|
|
|
|
|
|