A Dose-Escalating Study of R7159 Monotherapy in Patients With CD20+ Malignant Disease. - NCT00576758-21502 (Clinical Trial 195733)
Permalink: http://www.ClinicalConnection.com/exp/ExpandedPatientViewStudy195733.aspx
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CUMBERLAND |
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MD |
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21502 |
| Conditions: |
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Non-Hodgkin's Lymphoma |
| Purpose: |
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This study will investigate the safety and tolerability of weekly intravenous R7159
monotherapy, in patients with CD20+ malignant disease. Having identified the recommended
dose for further investigation, additional patients with relapsed CD20+ follicular NHL will
be randomized to receive either this dose of R7159, or MabThera (rituximab) 375mg/m2, given
as weekly infusions. The anticipated time on study treatment is 3-12 months, and the target
sample size is 100-500 individuals.
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| Study summary: |
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| Criteria: |
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Inclusion Criteria:
- adult patients, >=18 years of age;
- part 1 only: CD20+ malignant disease (lymphoma or CLL);
- part 2 only: relapsed CD20+ follicular non-Hodgkin's lymphoma.
Exclusion Criteria:
- prior use of any investigational monoclonal antibody within 6 months of study start;
- prior use of any anti-cancer vaccine;
- prior use of MabThera within 8 weeks of study entry;
- CNS lymphoma. |
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If you are interested in this clinical trial please use the contact information above. If you would like to get additional information about this clinical trial please visit ClinicalTrials.gov.
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| Data Source: |
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ClinicalTrials.gov |
| Date Processed: |
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November 4, 2009 |
Modifications to
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Only selected fields are shown, please use the link
above to view all information about this clinical trial. |
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Clinical trials are medical research studies designed to test the safety and/or
effectiveness of new drugs, devices, or treatments in humans. These studies are
conducted worldwide for a range of conditions and illnesses. Learn more about
clinical research and participating in a study at
About Clinical Trials.
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