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A Study Combining FOLFOX or FOLFIRI With AG-013736 or Avastin in Patients With Metastatic Colorectal Cancer After Failure of One First Line Regimen. - NCT00615056-34223(Clinical Trial 202503)



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City:  Englewood
State:  
FL
Zip Code: 34223
Conditions: Colorectal Neoplasms
Purpose: The study is designed to demonstrate that the combination of AG-013736 with either FOLFIRI or FOLFOX is superior to FOLFIRI or FOLFOX in combination with bevacizumab in delaying tumor progression in the second-line treatment of patients with metastatic colorectal cancer after failure of an irinotecan or oxaliplatin-containing first-line regimen
Study summary:
Criteria: Inclusion Criteria: - Histologically documented colorectal cancer plus one of the following: - Failure of one prior irinotecan- or oxaliplatin-containing regimen, or - Adjuvant refractory to irinotecan- or oxaliplatin-containing regimen. Exclusion Criteria: - Prior treatment in first line metastatic setting with more than one regimen - Prior irradiation of more than 25% of bone marrow.
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Data Source: ClinicalTrials.gov
Date Processed: February 16, 2010
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