A Dose Finding Study With I.V. Panobinostat (LBH589), Docetaxel, and Prednisone in Patients With Hormone Refractory Prostate Cancer - NCT00663832-89135 (Clinical Trial 216765)
Permalink: http://www.ClinicalConnection.com/exp/ExpandedPatientViewStudy216765.aspx
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| City: |
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Las Vegas |
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State:
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NV |
| Zip Code: |
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89135 |
| Conditions: |
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Prostate Cancer |
| Purpose: |
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This Phase Ib dose escalation study is designed to characterize the safety, tolerability and
preliminary efficacy of i.v. panobinostat (LBH589) in combination with docetaxel and
prednisone in the 1st line treatment of patients with hormone refractory prostate cancer.
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| Study summary: |
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| Criteria: |
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Inclusion criteria:
- HRPC patients
- Evidence of disease progression
- Self care, able to perform light work activities
- Willing to use contraception throughout the study and for 12 weeks after study
completion
Exclusion criteria:
- History of other cancers not curatively treated with no evidence of disease for more
than 5 years.
- Prior radiotherapy within 3 weeks of starting study treatment
- Prior radiopharmaceuticals (strontium, samarium).
- Impaired cardiac function
- Heart disease
- Liver or renal disease with impaired functions.
Other protocol-defined inclusion/exclusion criteria may apply |
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| Study is available at: |
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Nevada Cancer Institute
Las Vegas, NV 89135
United States
Primary Contact:
Sandra Lehr
Email: slahr@nvcancer.org
Phone: 702-822-5433
Secondary Contact:
Novartis Pharmaceuticals
Phone: +1-800-340-6843 |
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If you are interested in this clinical trial please use the contact information above. If you would like to get additional information about this clinical trial please visit ClinicalTrials.gov.
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| Data Source: |
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ClinicalTrials.gov |
| Date Processed: |
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March 15, 2010 |
Modifications to
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Only selected fields are shown, please use the link
above to view all information about this clinical trial. |
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Clinical trials are medical research studies designed to test the safety and/or
effectiveness of new drugs, devices, or treatments in humans. These studies are
conducted worldwide for a range of conditions and illnesses. Learn more about
clinical research and participating in a study at
About Clinical Trials.
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