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Efficacy of Losartan in Preventing Progression of COPD - NCT00720226-21205(Clinical Trial 232738)



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City:  Baltimore
State:  
MD
Zip Code: 21205
Conditions: COPD - Emphysema - Chronic Bronchitis - Smoking
Purpose: Evidence in animals shows that losartan can prevent or reverse inflammation and lung damage due to smoking. The goal of this study is to determine whether this drug which is also used to treat hypertension can stabilize or improve lung function in people who have from chronic obstructive pulmonary disease (COPD).
Study summary: Participants will be given either losartan in a dose of 50-100 mg per day for a period of one year. During that time, they will have lung function tests, breathing tests, and computed tomograms of the chest. These tests will determine whether there is inflammation in the lung and whether there is progressive involvement of the lung with COPD.
Criteria: Inclusion Criteria: - Adults with COPD who are either active or former smokers Exclusion Criteria: - Clinical requirement or history of intolerance of angiotensin receptor blockers, serious heart, liver, kidney, neurological disease.
Study is available at: Johns Hopkins Asthma and Allergy Center
Baltimore, MD 21205
United States

Primary Contact:
Teresa Concordia, RN
Email: tconcor1@jhmi.edu
Phone: 410-283-5728

Secondary Contact:
Gwen Leatherman, RN
Email: gleathe@jhmi.edu
Phone: 410 550-0800
If you are interested in this clinical trial please use the contact information above. If you would like to get additional information about this clinical trial please visit ClinicalTrials.gov.
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Data Source: ClinicalTrials.gov
Date Processed: March 22, 2011
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