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View Clinical Trial (Medical Research Study)

A Dose Ranging Study Of PF-00868554 In Combination With PEGASYS And COPEGUS In Patients With Chronic Hepatitis C Genotype 1 Infection - NCT00720434-32803 (Clinical Trial 232770)
Permalink: http://www.ClinicalConnection.com/exp/ExpandedPatientViewStudy232770.aspx



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City:  Orlando
State:  
FL
Zip Code: 32803
Conditions: Hepatitis C
Purpose: The purpose of this study is to further assess the potency of PF-00868554, an HCV polymerase inhibitor, in subjects chronically infected with HCV by evaluating the antiviral activity of PF-00868554 in combination with current standard of care therapy, pegylated interferon-alpha2a (PEGASYS) and ribavirin (COPEGUS).
Study summary:
Criteria: Inclusion Criteria: - Treatment naive (no prior treatment with IFN-a +/- RBV regimens. - Subjects who have discontinued IFN-a containing regimens after <2 weeks of therapy due to tolerability issues are considered treatment naive. - HCV RNA > 100,000 IU/mL at screening. - Genotype 1. - A diagnosis of chronic HCV infection for at least 6 months. Exclusion Criteria: - Evidence of acute or chronic infection with HIV or HBV. - Exposure within the previous three months to an investigational anti-HCV agent. - Evidence of severe or decompensated liver disease. - Subjects with liver disease unrelated to HCV infection.
Study is available at: Pfizer Investigational Site
Orlando, FL 32803
United States

Primary Contact:
Pfizer CT.gov Call Center
Phone: 1-800-718-1021
If you are interested in this clinical trial please use the contact information above. If you would like to get additional information about this clinical trial please visit ClinicalTrials.gov.
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Data Source: ClinicalTrials.gov
Date Processed: March 16, 2010
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Clinical trials are medical research studies designed to test the safety and/or effectiveness of new drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials.


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