A Crossover Study of the Acute Effects of Olanzapine in Healthy Volunteers - NCT00741026-17033 (Clinical Trial 238750)
Permalink: http://www.ClinicalConnection.com/exp/ExpandedPatientViewStudy238750.aspx
|
** Please review additional "Nearby Studies" on right ----->
|
|
 |
 |
|
| City: |
|
Hershey |
|
State:
|
|
PA |
| Zip Code: |
|
17033 |
| Conditions: |
|
Insulin Resistance - Diabetes Mellitus |
| Purpose: |
|
The purpose of this clinical research study is to examine the acute hormonal and metabolic
effects of the drug olanzapine, as well as appetite effects, in healthy volunteers. The
hypotheses to be tested are that: (1) Olanzapine rapidly attenuates plasma leptin and (2)
rapidly alters glucose tolerance in healthy volunteers. These questions will be answered by
having volunteers undergo two glucose tolerance tests in a crossover study design.
|
| Study summary: |
|
|
| Criteria: |
|
Inclusion Criteria:
- Healthy Volunteer
- Body Mass Index of 18.5-25 kilograms per square meter
- Must be able to swallow tablets
- Able to give informed consent
Exclusion Criteria:
- Any DSM-IV TR Axis I psychiatric disorder (except nicotine dependence)
- Presence of any medical disorder that may confound the assessment of relevant
biologic measures, including: significant organ system dysfunction, metabolic
diseases, type 1 diabetes mellitus, type 2 diabetes mellitus, pregnancy, endocrine
disease, coagulopathy, clinically significant anemia, or acute infection
- Subjects who have taken any antipsychotic medication within the last 6 months
- Personal or family history of seizures and/or cardiac arrhythmias |
|
|
|
| Study is available at: |
|
Penn State College of Medicine, Penn State Milton S. Hershey Medical Center
Hershey, PA 17033
United States
Primary Contact:
Shirlynn M Mottilla, R.N.
Email: smottill@gcrc.hmc.psu.edu
Phone: 717-531-5154
Secondary Contact:
Vance L Albaugh, B.S.
Email: valbaugh@psu.edu
Phone: 717-531-5344 |
|
|
If you are interested in this clinical trial please use the contact information above. If you would like to get additional information about this clinical trial please visit ClinicalTrials.gov.
|
| Trials Alerts: |
|
If you would like to be
notified of new clinical trials as they become available please
register for a free account.
|
|
| Data Source: |
|
ClinicalTrials.gov |
| Date Processed: |
|
November 16, 2009 |
Modifications to
this listing: |
|
Only selected fields are shown, please use the link
above to view all information about this clinical trial. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| |
|
|
| |
|
|
| |
|
|
| |
|
|
| |
|
|
| |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Clinical trials are medical research studies designed to test the safety and/or
effectiveness of new drugs, devices, or treatments in humans. These studies are
conducted worldwide for a range of conditions and illnesses. Learn more about
clinical research and participating in a study at
About Clinical Trials.
|
|
|
|
|