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Is Tuberculin Skin Testing Effective in Screening for Latent Tuberculosis in Patients With HIV? - NCT00763295-10305(Clinical Trial 244046)



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City:  Staten Island
State:  
NY
Zip Code: 10305
Conditions: Latent Tuberculosis - HIV Infections
Purpose: HIV infection highly increases the risk of progression of latent tuberculosis (TB) to active disease that therapy is recommended for all PPD-positive, HIV-infected patients, regardless of age. Sensitivity of the PPD testing is, however, dependent on a normal T cell function. Therefore, an accurate and reliable method for detection of latent tuberculosis in patients with HIV is urgently needed. This prospective study will examine the utility of interferon-gamma (IFN-γ) based assay, T-SPOT.TB,for detection of TB in HIV-infected individuals.
Study summary:
Criteria: Inclusion Criteria - adult individuals with confirmed HIV infection Exclusion Criteria: - Patients who are on INH treatment - Patients who have a positive PPD test within 1 year of study enrollment - Individuals with blistering or ulcerating skin disorder - Pregnant women - Patients who were given blood transfusion within 6 weeks prior to enrollment
Study is available at: Staten Island University Hospital
Staten Island, NY 10305
United States

Primary Contact:
Anita B Szerszen, DO
Email: aszerszen@siuh.edu
Phone: 718-226-6387

Secondary Contact:
Anita B Szerszen, DO
Email: aszerszen@siuh.edu
Phone: 718 226 6387
If you are interested in this clinical trial please use the contact information above. If you would like to get additional information about this clinical trial please visit ClinicalTrials.gov.
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Data Source: ClinicalTrials.gov
Date Processed: March 22, 2011
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