A Phase II Study of Dasatinib in Children and Adolescents With Relapsed or Refractory Leukemia - NCT00777036-85016 (Clinical Trial 248653)


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A Phase II Study of Dasatinib in Children and Adolescents With Relapsed or Refractory Leukemia - NCT00777036-85016 (Clinical Trial 248653)
Permalink: http://www.ClinicalConnection.com/exp/ExpandedPatientViewStudy248653.aspx

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City:

Phoenix

State:

Zip Code:

85016

Conditions:

Leukemia

Purpose:

The purpose of this study is to find out if dasatinib is effective in children and adolescents with chronic myeloid leukemia (CML) or acute lymphoblastic leukemia (ALL) who prove resistant or intolerant to imatinib or relapsed after imatinib. The side effects this oral investigational drug may have in children and adolescents will also be studied

Study summary:

Criteria:

Inclusion Criteria: - Ph+ CML in chronic, accelerated or blast phase or Ph+ ALL with imatinib-resistant disease or intolerance - Lansky or Karnofsky scale > 50 - Life expectancy >= 12 weeks - Adequate hepatic renal function Exclusion Criteria: - Eligibility for potentially-curative therapy including hematopoietic stem-cell transplantation - Symptomatic CNS involvement (other than signs and symptoms caused by leptomeningeal disease) - Isolated extramedullary disease - Prior therapy with dasatinib

Study is available at:

Phoenix Children'S Hospital
Phoenix, AZ 85016
United States

Primary Contact:
Jessica Boklan, Site 005
Phone: 602-546-5067

Secondary Contact:
For participation information at a USA site use a phone number below. For site information outside the USA please email:
Email: Clinical.Trials@bms.com

If you are interested in this clinical trial please use the contact information above. If you would like to get additional information about this clinical trial please visit ClinicalTrials.gov.

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Data Source:

ClinicalTrials.gov

Date Processed:

November 16, 2009

Modifications to
this listing:

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Clinical trials are medical research studies designed to test the safety and/or effectiveness of new drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials.


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