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Ciracadian Ocular Perfusion and Ocular Blood Flow - NCT00800540-76134(Clinical Trial 256920)



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City:  Fort Worth
State:  
TX
Zip Code: 76134
Conditions: Glaucoma
Purpose: Compare the short term effects of two IOP-lowering medications on ocular perfusion pressure, ocular blood flow, circadian IOP and blood pressure in patients with glaucoma.
Study summary:
Criteria: Inclusion Criteria: - 18 years of age or older - Either sex - Open-Angle Glaucoma in at least one eye - Requiring more than one IOP lowering medication - Mean IOP ≥ 23 mmHg at one time point during Eligibility/Baseline Visit (7 IOP measurements) and ≤ 32 mmHg at all time points at screening, safety, eligibility/Period 1 Baseline Visits Exclusion Criteria: - Severe central visual field loss in either eye - Shaffer angle grade < III - Cup/disc ratio > 0.8 in either eye - Previous glaucoma surgery - Intraocular surgery < 3 months - Best-corrected VA > 0,6 logMAR - Contact lens wear - Allergy/hypersensitivity to study medication - Glucocorticoid must be discontinued 4 weeks prior to the screening visit and not be used during the study - Cardiovascular disease or uncontrolled hepatic, renal diseases that would require use of medications that could affect IOP or blood pressure - Medication that could affect IOP or Blood Pressure - Recent use (< 4 weeks prior to the study) of aspirin (> 1 gram) - Bronchial asthma or severe chronic obstructive pulmonary disease - Diabetic retinopathy - Any abnormality preventing reliable tonometry
Study is available at: Contact Alcon Call Center For Trial Locations
Fort Worth, TX 76134
United States

Primary Contact:
Alcon Call Center
Phone: 1-888-451-3937
If you are interested in this clinical trial please use the contact information above. If you would like to get additional information about this clinical trial please visit ClinicalTrials.gov.
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Data Source: ClinicalTrials.gov
Date Processed: March 22, 2011
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