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Contingency Management for Smoking in Substance Abusers - NCT00807742-02903(Clinical Trial 259109)



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City:  Providence
State:  
RI
Zip Code: 02903
Conditions: Substance Abuse
Purpose: The aim of this study is to determine whether contingent reinforcement for smoking abstinence, compared to noncontingent reinforcement, increases the effectiveness of brief counseling and nicotine replacement on smoking abstinence of substance abusers in residential treatment.
Study summary: Substance abusers have a high prevalence and rate of smoking with little success in quitting, so stronger approaches are needed to encourage attempts to quit smoking. The aim of this study is to determine whether contingent reinforcement for smoking abstinence (CM), compared to noncontingent reinforcement (NR), increases the effectiveness of brief counseling and nicotine replacement on smoking abstinence of substance abusers in residential treatment. The proposed study will be a 2-group design in which up to 274 substance abusers who smoke 10 or more cigarettes per day receive brief advice (4 sessions) and nicotine replacement (NRT) (8 weeks), and are randomized to 19 days of CM for smoking vs. a matched NR condition. The brief advice is adapted slightly for sobriety settings. Point-prevalence abstinence will be assessed at 1, 3, 6 and 12 months after starting treatment. Secondary aims evaluate effects of CM on substance use outcomes and potential mediators of effects on outcome, including within-treatment abstinence, motivation level and tolerance for smoking discomfort. The significance is to add knowledge about the most effective ways to maximize smoking cessation among substance abusers, important given that no methods are known to work with this population.
Criteria: Inclusion Criteria: - diagnosis of substance abuse or dependence by DSM-IV criteria - in residential treatment at one particular agency - currently smoking at least 10 cigarettes per day for the past 6 months Exclusion Criteria: - hallucinating or delusional or marked organic impairment (to the point of impairing ability to understand informed consent) according to medical records - current use of nicotine replacement therapy, Zyban, or any other smoking cessation treatment - medical exclusions for NRT: pregnant or nursing; treatment in the last 3 months for unstable angina, severe congestive heart failure, uncontrolled hypertension; lung cancer; supplemental oxygen; history of adverse reactions to NRT; allergies to adhesive; or any severe skin disease that requires treatment (e.g., psoriasis or eczema).
Study is available at: Brown University, Center for Alcohol and Addiction Studies
Providence, RI 02903
United States

Primary Contact:
Rebecca Uth, M.A.
Email: rebecca_uth@brown.edu
Phone: (401) 863-6608
If you are interested in this clinical trial please use the contact information above. If you would like to get additional information about this clinical trial please visit ClinicalTrials.gov.
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Data Source: ClinicalTrials.gov
Date Processed: March 22, 2011
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