View Clinical Trial (Medical Research Study)
Cognitive Training to Enhance VA Work Program Outcomes - NCT00829400-06516(Clinical Trial 265702)
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| City: |
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West Haven |
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State:
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CT |
| Zip Code: |
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06516 |
| Conditions: |
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Mental Illness - Schizophrenia - Depression - PTSD - Bipolar Disorder |
| Purpose: |
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The purpose of this study is to determine whether augmenting work services with cognitive
remediation can improve vocational outcomes for psychiatrically disabled participants in VA
work services.
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| Study summary: |
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Background: Our previous RR&D funded study demonstrated significantly better vocational
outcomes for people with schizophrenia when cognitive training supplemented their
participation in Incentive Therapy. We have found in a subsequent NIMH funded study
involving cognitive training and supported employment that competitive employment outcomes
were better for those who received cognitive training. Moreover, we found that patients with
the poorest community function at intake were very unlikely to obtain competitive employment
unless they received the cognitive training. The current study will test the effectiveness
of cognitive training by extending it to a broader range of VA patients with psychotic
disorders participating in all types of VA work services currently available, including
Incentive Therapy, Compensated Work Therapy, and Supported Employment. We plan to offer it
to any patient with a psychotic disorder who is unlikely to obtain competitive employment
without additional services. We will also compare two types of cognitive training to
determine whether cognitive game software works as well narrowly focused cognitive
exercises.
Design and Method: This is a randomized clinical trial in which 80 VA patients referred for
VA work services and who meet criteria for psychotic disorder and impaired community
function will be randomized to one of two types of cognitive training. There will be two
conditions with approximately 40 subjects per condition. Intake procedures will include
psychosocial, neuropsychological, and psychiatric assessments. These assessments will be
repeated at 6-months and 12 month follow-up. Cognitive training will consist of
computer-based cognitive exercises of attention, memory and problem-solving and a weekly
group that focuses on improving work behaviors. One of the computer-based systems employs
engaging cognitive game software and the other uses specially designed exercises that
narrowly focus on discrete cognitive processes. Work services will be provided as usual to
both conditions. Primary endpoints are measures of productive activity including obtaining
competitive employment, total hours worked, and money earned. Secondary endpoints include
neuropsychological, quality of life and health status changes. The study will be for three
years. |
| Criteria: |
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Inclusion Criteria:
- Participant in VA work services
- Chronic and disabling psychiatric illness
Exclusion Criteria:
- Neurological Disease that may affect cognition
- Primary substance abuse
- Developmental Disability |
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| Study is available at: |
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VA Connecticut Healthcare System
West Haven, CT 06516
United States
Primary Contact:
Morris D Bell, PhD
Email: morris.bell@yale.edu
Phone: 203-932-5711 |
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If you are interested in this clinical trial please use the contact information above. If you would like to get additional information about this clinical trial please visit ClinicalTrials.gov.
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| Data Source: |
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ClinicalTrials.gov |
| Date Processed: |
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March 22, 2011 |
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