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4D PET/CT Imaging in Lung and Colorectal Cancer With Liver Metastasis - NCT00862680-77030(Clinical Trial 278547)



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City:  Houston
State:  
TX
Zip Code: 77030
Conditions: Colorectal Cancer - Lung Cancer - Liver Cancer
Purpose: The objective of this proposal is to study the impact of 4D Positron Emission Tomography/Computed Tomography (PET/CT) imaging on the evaluation and staging of lung and colorectal cancer. This research project has three goals: 1. Acquire 4D PET/CT data on 26 lung and/or colorectal patients with specific inclusion criteria. 2. Compare lesion SUVmax between gated and non-gated PET scans. 3. Evaluate the impact of the difference in the maximum standardized uptake value (SUVmax) on lesion detectability and staging.
Study summary: Routine PET/CT scans are taken while patients are breathing normally. The motions made by breathing can reduce the image quality of the scan. Minimizing the effects of this motion by taking the images and processing the scans differently may improve the image quality. The PET/CT Scan: If you agree to take part in this study, a small plastic box (weighing less than 1 ounce) will be placed on your abdominal area before your routine PET/CT scan. This box is used to track your breathing motion. This information will be used to help process the scan. Your PET/CT scan will be performed as usual. During the scan, the researchers will focus on your lower chest/upper abdomen (areas that experience breathing motion). Having to focus on this area might extend the scan by up to 12 minutes. Length of Study: Your participation on this study will be complete when your scheduled PET/CT scan is complete. This is an investigational study. The imaging focused on your lower chest/upper abdomen during the scan is investigational. Up to 26 patients will take part in this study. All will be enrolled at M. D. Anderson.
Criteria: Inclusion Criteria: 1. Patients with suspected colorectal cancer with nodules in the lung or liver (1-2 cm in diameter) will be eligible for this study. 2. Patients with suspected lung cancer with nodules in the lung or liver (1-2 cm in diameter) will be eligible for this study. Exclusion Criteria: 1. Pediatric patients (younger than 18 years) will be excluded. 2. Patients that cannot tolerate being scanned for an additional 12 minutes with arms above their head will be excluded.
Study is available at: UT MD Anderson Cancer Center
Houston, TX 77030
United States

Primary Contact:
Osama R. Mawlawi, PhD
Phone: 713-563-2711
If you are interested in this clinical trial please use the contact information above. If you would like to get additional information about this clinical trial please visit ClinicalTrials.gov.
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Data Source: ClinicalTrials.gov
Date Processed: March 23, 2011
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