A Phase 2 Open Label Trial of SGN-35 for Systemic Anaplastic Large Cell Lymphoma - NCT00866047-75246 (Clinical Trial 279499)
Permalink: http://www.ClinicalConnection.com/exp/ExpandedPatientViewStudy279499.aspx
|
** Please review additional "Nearby Studies" on right ----->
|
|
 |
 |
|
| City: |
|
Dallas |
|
State:
|
|
TX |
| Zip Code: |
|
75246 |
| Conditions: |
|
Lymphoma, Non-Hodgkin - Lymphoma, Large-Cell, Anaplastic |
| Purpose: |
|
This is a single-arm, open-label, multicenter, clinical trial to evaluate the efficacy and
safety of SGN-35 as a single agent in patients with relapsed or refractory ALCL.
|
| Study summary: |
|
|
| Criteria: |
|
Inclusion Criteria:
- Patients with relapsed or refractory systemic ALCL who have previously received front
line chemotherapy.
- Documented anaplastic lymphoma kinase (ALK) status.
- Histologically-confirmed CD30-positive disease; tissue from the most recent post
diagnostic biopsy of relapsed/refractory disease must be available for confirmation
of CD30 expression via slides or tumor block.
- Fluorodeoxyglucose (FDG)-avid and measurable disease of at least 1.5 cm as documented
by both PET and spiral CT.
- Received any previous ASCT at least 12 weeks (3 months) prior.
- At US sites patients greater than or equal to 12 years of age may be enrolled. At
non-US sites patients must be greater than or equal to 18 years of age.
Exclusion Criteria:
- Previous treatment with SGN-35.
- Previously received an allogeneic transplant.
- Patients with current diagnosis of primary cutaneous ALCL (patients who have
transformed to systemic ALCL are eligible).
- Known cerebral/meningeal disease. |
|
|
|
| Study is available at: |
|
Baylor Sammons Cancer Center
Dallas, TX 75246
United States
Primary Contact:
Ryan Woelfel
Email: ryanwo@baylorhealth.edu
Phone: 214-820-1970
Secondary Contact:
Terri Lowe
Email: clinicaltrials@seagen.com
Phone: 866-333-7436 |
|
|
If you are interested in this clinical trial please use the contact information above. If you would like to get additional information about this clinical trial please visit ClinicalTrials.gov.
|
| Trials Alerts: |
|
If you would like to be
notified of new clinical trials as they become available please
register for a free account.
|
|
| Data Source: |
|
ClinicalTrials.gov |
| Date Processed: |
|
November 16, 2009 |
Modifications to
this listing: |
|
Only selected fields are shown, please use the link
above to view all information about this clinical trial. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| |
|
|
| |
|
|
| |
|
|
| |
|
|
| |
|
|
| |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Clinical trials are medical research studies designed to test the safety and/or
effectiveness of new drugs, devices, or treatments in humans. These studies are
conducted worldwide for a range of conditions and illnesses. Learn more about
clinical research and participating in a study at
About Clinical Trials.
|
|
|
|
|