A Case Control Study to Define Clinical, Immunologic and Radiographic Features of the Aromatase Inhibitor Arthralgia Syndrome - NCT00890058-20007 (Clinical Trial 289358)
Permalink: http://www.ClinicalConnection.com/exp/ExpandedPatientViewStudy289358.aspx
|
** Please review additional "Nearby Studies" on right ----->
|
|
 |
 |
|
| City: |
|
Washington |
|
State:
|
|
DC |
| Zip Code: |
|
20007 |
| Conditions: |
|
Arthralgia Syndrome - Arthritis - Synovitis |
| Purpose: |
|
The CIRAS study will investigate postmenopausal breast cancer patients with hand pain and
compare those receiving aromatase inhibitors (cases) to breast cancer patients with hand
pain not receiving aromatase inhibitors (controls) in order assess whether this syndrome is
an inflammatory arthritis.
|
| Study summary: |
|
This study is for women with post-menopausal breast cancer and hand pain. Patients do not
need to be taking aromatase inhibitors to be eligible for the study. We want to study the
joint findings in patients with hand pain and breast cancer undergoing treatment with
aromatase inhibitor medications and compare them to patients with hand pain and breast
cancer not treated with these medications.
Aromatase inhibitor drugs are used in certain types of breast cancer to reduce the risk of
cancer returning after treatment. One of the side effects of aromatase inhibitors is the
development of joint pain, a complication known as the Arthralgia Syndrome. The cause of the
Arthralgia Syndrome is not known, but we suspect that the pain may be due to inflammation in
the joints. Currently, the only effective treatment is to stop the aromatase inhibitor, and
so affected patients may miss out on an otherwise useful treatment to prevent return of
their cancer.
Post-menopausal patients with breast cancer and hand pain can enroll in the study. Patients
will be asked to come for a separate visit which will take about half a day. |
| Criteria: |
|
Inclusion Criteria:
1. Postmenopausal women aged over 18 with stage I-III breast cancer undergoing treatment
at the Lombardi Cancer Center.
2. Presence of hand pain
3. No active signs of ongoing malignant disease
Exclusion Criteria:
1. Known autoimmune disease for example, rheumatoid arthritis, systemic lupus
erythematosis, polymyalgia rheumatica, or seronegative arthritis.
2. Age <18
3. Unable to complete informed consent process |
|
|
|
| Study is available at: |
|
Georgetown University Hospital
Washington, DC 20007
United States
Primary Contact:
Victoria K Shanmugam, MD
Email: vks4@gunet.georgetown.edu
Phone: 202-444-6200 |
|
|
If you are interested in this clinical trial please use the contact information above. If you would like to get additional information about this clinical trial please visit ClinicalTrials.gov.
|
| Trials Alerts: |
|
If you would like to be
notified of new clinical trials as they become available please
register for a free account.
|
|
| Data Source: |
|
ClinicalTrials.gov |
| Date Processed: |
|
November 16, 2009 |
Modifications to
this listing: |
|
Only selected fields are shown, please use the link
above to view all information about this clinical trial. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| |
|
|
| |
|
|
| |
|
|
| |
|
|
| |
|
|
| |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Clinical trials are medical research studies designed to test the safety and/or
effectiveness of new drugs, devices, or treatments in humans. These studies are
conducted worldwide for a range of conditions and illnesses. Learn more about
clinical research and participating in a study at
About Clinical Trials.
|
|
|
|
|