View Clinical Trial (Medical Research Study)
The Relative Prevalence and Severity of Autonomic Nervous System Dysfunction - NCT00919347-35233(Clinical Trial 297631)
ClinicalConnection.com has recently undergone an update and this page may no longer be up-to-date. Please Search For Clinical Trials to view the most current clinical trials listings.
| City: |
|
Birmingham |
|
State:
|
|
AL |
| Zip Code: |
|
35233 |
| Conditions: |
|
Cardiovascular Autonomic Neuropathy - Diabetic Autonomic Neuropathy - Autonomic Dysfunction |
| Purpose: |
|
The purpose of this study is to measure the prevalence and severity of cardiac autonomic
neuropathy (CAN), diabetic autonomic neuropathy (DAN) which in non-diabetics is termed
advanced nervous system (ANS) dysfunction, and autonomic dysfunction as well as the overall
sympathovagal balance (SB) in the CEFH population of diabetic patients versus non-diabetic
patients undergoing elective vitreoretinal surgery.
|
| Study summary: |
|
The purpose of this study is to measure the prevalence and severity of cardiac autonomic
neuropathy (CAN), diabetic autonomic neuropathy (DAN) which in non-diabetics is termed
advanced nervous system (ANS) dysfunction, and autonomic dysfunction as well as the overall
sympathovagal balance (SB) in the CEFH population of diabetic patients versus non-diabetic
patients undergoing elective vitreoretinal surgery. |
| Criteria: |
|
Inclusion Criteria:
- Type I and Type II Diabetic patients 19 or older who are scheduled for elective
surgery to improve vision impaired by diabetic retinopathy
- Patients scheduled during the same time period without diabetes for retinal surgery
will serve as an age and gender matched reference group to undergo the non-invasive
ANS testing on the day of surgery
Exclusion Criteria:
- Inability to stand will only do baseline, deep breathing and Valsalva portions (A-D)
of the testing as described in section 8.1
- Patients with syncope on standing will only do portions A-D of the test
- Inability to cooperate with deep breathing and Valsalva
- Tracheoscopy or otherwise not able to perform a Valsalva
- Not desiring to participate after informed consent
- Known history of idiopathic dysautonomia
- Pulmonary difficulties associated with hyperventilation, including acute URI
- Pacemaker dependent
- Persistently high intraocular pressure despite treatment
- Atrial fibrillation
- Ventricular arrhythmias greater than 10 beats per minute
- Taking MAO inhibitors |
|
|
|
| Study is available at: |
|
Callahan Eye Foundation Hospital
Birmingham, AL 35233
United States
Primary Contact:
Jeff Worrell, BSN
Email: jworrell@uab.edu
Phone: 205-975-2098
Secondary Contact:
Jeff Worrell, BSN
Email: jworrell@uab.edu
Phone: 205-975-2098 |
|
|
If you are interested in this clinical trial please use the contact information above. If you would like to get additional information about this clinical trial please visit ClinicalTrials.gov.
|
| Trials Alerts: |
|
If you would like to be
notified of new clinical trials as they become available please
register for a free account.
|
|
| Data Source: |
|
ClinicalTrials.gov |
| Date Processed: |
|
March 23, 2011 |
Modifications to
this listing: |
|
Only selected fields are shown, please use the link
above to view all information about this clinical trial. |
|
|
|
|
|
|
|
|