A Phase 2 Study Of The 24-Hour Intraocular Pressure Lowering And Systemic Exposure Of PF-04217329 - NCT00934089-90247 (Clinical Trial 301013)
Permalink: http://www.ClinicalConnection.com/exp/ExpandedPatientViewStudy301013.aspx
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| City: |
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Gardena |
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State:
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CA |
| Zip Code: |
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90247 |
| Conditions: |
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Glaucoma, Open-Angle - Ocular Hypertension |
| Purpose: |
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This study will characterize the effect of PF-04217329, alone and in combination with
latanoprost, on circadian intraocular pressure and blood pressure in glaucoma patients.
Blood samples will be collected to measure the amount of active metabolite of PF-04217329 in
the plasma following dosing.
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| Study summary: |
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| Criteria: |
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Inclusion Criteria:
- Diagnosis of primary open-angle glaucoma or ocular hypertension in one or both eyes
- IOP of at least 22 mmHg and not more than 30 mmHg in either eye at 8 AM after
discontinuing previous glaucoma treatment
- Visual acuity correctable to 20/100 or better in each eye.
Exclusion Criteria:
- Closed/barely open anterior chamber angle or a history of acute angle closure in
either eye.
- Diagnosis of a clinically significant or progressive retinal disease (eg, diabetic
retinopathy, macular degeneration) in either eye.
- Advanced glaucoma or a history of severe central visual field loss in either eye.
- History of ocular surgery or trauma in either eye within 6 months of the screening
visit.
- History of ocular infection, ocular inflammation, or laser surgery in either eye
within 3 months of the screening visit. |
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| Study is available at: |
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Pfizer Investigational Site
Gardena, CA 90247
United States
Primary Contact:
Pfizer CT.gov Call Center
Phone: 1-800-718-1021 |
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If you are interested in this clinical trial please use the contact information above. If you would like to get additional information about this clinical trial please visit ClinicalTrials.gov.
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| Data Source: |
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ClinicalTrials.gov |
| Date Processed: |
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March 16, 2010 |
Modifications to
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Only selected fields are shown, please use the link
above to view all information about this clinical trial. |
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Clinical trials are medical research studies designed to test the safety and/or
effectiveness of new drugs, devices, or treatments in humans. These studies are
conducted worldwide for a range of conditions and illnesses. Learn more about
clinical research and participating in a study at
About Clinical Trials.
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