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Study of Bone Disease in Older HIV-infected Adults - NCT00935935-60612(Clinical Trial 301232)



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City:  Chicago
State:  
IL
Zip Code: 60612
Conditions: Osteopenia - Osteoporosis - HIV Infection - Aging - HIV Infections
Purpose: This study will look to see if there are changes in the blood cells that are associated with bone disease and sort out effects that are due to the HIV virus itself, the medications and see if faster aging occurs in the cells of HIV infected persons. Bone disease will be measured by a special X-ray called a DEXA scan. A DEXA scan is used by doctors to see if someone has normal bone mass for their age or if there is thinning of the bones. The purposes of this study are: - to learn how common bone disease is in HIV infected patients over the age of 50 years that receive their care at the CORE Center - to see what are the common causes of bone disease in older HIV infected persons - to see if there are differences in blood cells and levels of cytokines in patients who do or do not have bone disease, as this may help researchers determine the cause of bone disease.
Study summary:
Criteria: Inclusion Criteria: - HIV-1 infection documented by ELISA and confirmed by western blot - Treatment with antiretroviral drugs for at least 12 months - Age 50-70 years - CD4 count > 350 cells/mm3 for at least 6 months - HIV-RNA undetectable (< 75 copies/ml for at least 6 months) Exclusion Criteria: - Known bone disease (primary or metastatic malignancy, osteomalacia) - Treatment for bone disease (bisphosphonates, calcitonin, strontium, sodium fluoride, synthetic PTH, or high-dose vitamin D [> 800 IU daily]).
Study is available at: Ruth M Rothstein CORE Center
Chicago, IL 60612
United States

Primary Contact:
Mieoak Bahk
Email: mbahk@corecenter.org
Phone: 312-572-4543
If you are interested in this clinical trial please use the contact information above. If you would like to get additional information about this clinical trial please visit ClinicalTrials.gov.
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Data Source: ClinicalTrials.gov
Date Processed: March 23, 2011
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