View Clinical Trial (Medical Research Study)
Trial Comparing Neomycin to Rifaximin Plus Neomycin in the Treatment of Methane Positive Subjects With Constipation Predominant Irritable Bowel Syndrome (C-IBS) - NCT00945334-90048(Clinical Trial 303198)
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Los Angeles |
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State:
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CA |
| Zip Code: |
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90048 |
| Conditions: |
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Irritable Bowel Syndrome Characterized by Constipation |
| Purpose: |
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In this study the investigators aim to compare the efficacy of neomycin to a combination of
rifaximin and neomycin in the treatment of C-IBS subjects with methane on their breath test.
This study will be conducted in collaboration with Dr. John DiBaise at the Mayo Clinic in
Scottsdale, AZ.
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| Study summary: |
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| Criteria: |
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Inclusion Criteria:
- Rome III positive IBS subjects (18-75 years of age) -Meet criteria for constipation
predominant IBS symptoms including ≤ 3 bm per week with hard or lumpy stools.
- Presence of detectable methane on single breath sample (≥ 3ppm).
- If subjects are ≥ 50 years old, a colonoscopy had to have been completed within the
past 5 years.
Exclusion Criteria:
- Subjects with history of intestinal surgery (except appendectomy or cholecystectomy)
- Recent antibiotic use (within the last 30 days)
- Subjects with known pelvic floor dysfunction
- Pregnancy
- Creatinine level > 1.4
- Poorly controlled/uncontrolled significant medical condition that would interfere
with study procedures
- Subjects with hearing loss and/or tinnitus
- History of bowel obstruction
- History of celiac disease
- History of inflammatory bowel disease
- Cirrhosis
- Diabetes |
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| Study is available at: |
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Cedars-Sinai Medical Center Los Angeles, CA 90048 United States
Primary Contact: Kathleen Shari Chua, BA Email: Chuak@cshs.org Phone: 310-423-3792
Secondary Contact: Kathleen Shari Chua, BA Email: Chuak@cshs.org Phone: (310)423-3792 |
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If you are interested in this clinical trial please use the contact information above. If you would like to get additional information about this clinical trial please visit ClinicalTrials.gov.
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| Data Source: |
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ClinicalTrials.gov |
| Date Processed: |
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March 23, 2011 |
Modifications to
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