Welcome To Clinical Connection Our clinical trials database is updated daily Over 250,000 individuals are currently being connected to clinical trials by ClinicalConnection.com!   Trials Alerts Trials Search Health Forum Health News RSS Intro Clinics & Sponsors Member Login	View Clinical Trial (Medical Research Study) Trial Comparing Neomycin to Rifaximin Plus Neomycin in the Treatment of Methane Positive Subjects With Constipation Predominant Irritable Bowel Syndrome (C-IBS) - NCT00945334-90048 (Clinical Trial 303198) Permalink: http://www.ClinicalConnection.com/exp/ExpandedPatientViewStudy303198.aspx ** Please review additional "Nearby Studies" on right -----> City:  Los Angeles State:   CA Zip Code: 90048 Conditions: Constipation-predominant Irritable Bowel Syndrome Purpose: In this study the investigators aim to compare the efficacy of neomycin to a combination of rifaximin and neomycin in the treatment of C-IBS subjects with methane on their breath test. This study will be conducted in collaboration with Dr. John DiBaise at the Mayo Clinic in Scottsdale, AZ. Study summary: Criteria: Inclusion Criteria: - Rome III positive IBS subjects (18-75 years of age) -Meet criteria for constipation predominant IBS symptoms including ≤3 bm per week with hard or lumpy stools - Presence of detectable methane on single breath sample (≥3ppm). - If subjects are ≥50 years old, a colonoscopy had to have been completed within the past 5 years. Exclusion Criteria: - Subjects with history of intestinal surgery (except appendectomy or cholecystectomy) - Recent antibiotic use (within the last 30 days) - Subjects with known pelvic floor dysfunction - Pregnancy - Creatinine level >1.4 - Poorly controlled/uncontrolled significant medical condition that would interfere with study procedures - Subjects with hearing loss and/or tinnitus - History of bowel obstruction - History of celiac disease - History of inflammatory bowel disease - Cirrhosis - Diabetes Study is available at: Cedars-Sinai Medical Center Los Angeles, CA 90048 United States Primary Contact: Kathleen Shari Chua, BA Email: Chuak@cshs.org Phone: 310-423-3792 Secondary Contact: Kathleen Shari Chua, BA Email: Chuak@cshs.org Phone: (310)423-3792 If you are interested in this clinical trial please use the contact information above. If you would like to get additional information about this clinical trial please visit ClinicalTrials.gov. Trials Alerts: If you would like to be notified of new clinical trials as they become available please register for a free account. Data Source: ClinicalTrials.gov Date Processed: March 16, 2010 Modifications to this listing: Only selected fields are shown, please use the link above to view all information about this clinical trial.                 Clinical trials are medical research studies designed to test the safety and/or effectiveness of new drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials.	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