Welcome To Clinical Connection Our clinical trials database is updated daily Over 250,000 individuals are currently being connected to clinical trials by ClinicalConnection.com!   Trials Alerts Trials Search Health Forum Health News RSS Intro Clinics & Sponsors Member Login	View Clinical Trial (Medical Research Study) A Study to Evaluate the Efficacy and Safety of Arbaclofen Placarbil (XP19986) as Adjunctive Therapy in Subjects With Gastroesophageal Reflux Disease (GERD) - NCT00978016-92801 (Clinical Trial 331173) Permalink: http://www.ClinicalConnection.com/exp/ExpandedPatientViewStudy331173.aspx ** Please review additional "Nearby Studies" on right -----> City:  Anaheim State:   CA Zip Code: 92801 Conditions: Gastroesophageal Reflux Disease Purpose: The purpose of the study is to evaluate efficacy and safety of arbaclofen placarbil (XP19986) versus placebo as adjunctive therapy in subjects with troublesome GERD symptoms despite therapy with approved doses of a Proton Pump Inhibitor (PPI). Study summary: Criteria: Inclusion Criteria: 1. confirmed diagnosis of GERD by a gastroenterologist 2. minimum of 3 months of GERD symptoms prior to screening. 3. currently taking an FDA approved dose of PPI therapy for symptomatic GERD for at least 4 weeks prior to screening 4. experienced partial relief of GERD symptoms while receiving approved dose and regimen of PPI therapy 5. experienced GERD symptoms, defined as heartburn (with or without regurgitation or other GERD symptoms) on ≥ 3 days during the week prior to screening Exclusion Criteria: 1. evidence of erosive esophagitis or erosive gastritis on upper gastrointestinal endoscopy during screening 2. has not experienced any GERD symptom improvement after an adequate course of PPI treatment (at least 2 weeks) 3. unstable or severe medical condition Study is available at: Anaheim, CA 92801 United States Primary Contact: Phone: 910-558-2856 Secondary Contact: Study Manager Phone: 910-558-2856 If you are interested in this clinical trial please use the contact information above. If you would like to get additional information about this clinical trial please visit ClinicalTrials.gov. Trials Alerts: If you would like to be notified of new clinical trials as they become available please register for a free account. Data Source: ClinicalTrials.gov Date Processed: February 17, 2010 Modifications to this listing: Only selected fields are shown, please use the link above to view all information about this clinical trial.                 Clinical trials are medical research studies designed to test the safety and/or effectiveness of new drugs, devices, or treatments in humans. These studies are conducted worldwide for a range of conditions and illnesses. Learn more about clinical research and participating in a study at About Clinical Trials.	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